| Title: |
Maintaining the gluten-free diet: The key to improve glycemic metrics in youths with type 1 diabetes and celiac disease |
| Authors: |
Mozzillo E.; Marigliano M.; Cuccurullo I.; Berchielli F.; Auricchio R.; Maffeis C.; Rosanio F. M.; Iafusco D.; Pedrolli C.; Pertile R.; Delvecchio M.; Passanisi S.; Salzano G.; Di Candia F.; Franceschi R. |
| Contributors: |
Mozzillo, E.; Marigliano, M.; Cuccurullo, I.; Berchielli, F.; Auricchio, R.; Maffeis, C.; Rosanio, F. M.; Iafusco, D.; Pedrolli, C.; Pertile, R.; Delvecchio, M.; Passanisi, S.; Salzano, G.; Di Candia, F.; Franceschi, R. |
| Publication Year: |
2024 |
| Collection: |
IRIS Università degli Studi di Napoli Federico II |
| Subject Terms: |
Celiac disease; Glucose control; Maintaining GFD; Type1 diabetes mellitus |
| Description: |
Aims: Gluten-free diets (GFD) were considered as high glycemic index and/or high content of saturated fats; this could affect keeping good metabolic control in individuals with both type 1 diabetes (T1D) and celiac disease (CD). Our objective was to analyze time in range and other continuous glucose monitoring (CGM) metrics with real-time CGM systems, in youths with T1D and CD, compared to those with T1D only. Methods: An observational case-control study, comparing youths aged 8-18 years with T1D and CD, with people with T1D only was performed. The degree of maintaining GFD was assessed through anti-tissue transglutaminase antibodies and dietary interview, and maintaining Mediterranean diet through the KIDMED questionnaire. Results: 86 youths with T1D and CD, 167 controls with T1D only, were included in the study and the two groups reported similar real-time CGM metrics. Among the first group, 29 % were not completely maintaining GFD and compared to people with T1D only they showed higher hyperglycemia rates (% time above range: 38.72 ± 20.94 vs 34.34 ± 20.94; P = 0.039). Conclusions: Individuals with T1D and CD who maintain GFD presented similar glucose metrics compared to youths with T1D only. Individuals not strictly maintaining GFD presented higher hyperglycemia rates. |
| Document Type: |
article in journal/newspaper |
| Language: |
English |
| Relation: |
info:eu-repo/semantics/altIdentifier/wos/WOS:001155980700001; volume:207; journal:DIABETES RESEARCH AND CLINICAL PRACTICE; https://hdl.handle.net/11588/955510 |
| DOI: |
10.1016/j.diabres.2023.111074 |
| Availability: |
https://hdl.handle.net/11588/955510; https://doi.org/10.1016/j.diabres.2023.111074 |
| Rights: |
info:eu-repo/semantics/openAccess ; license:Non specificato ; license uri:na |
| Accession Number: |
edsbas.CF69B3B0 |
| Database: |
BASE |