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Male partner circumcision associated with lower trichomonas vaginalis incidence among pregnant and postpartum kenyan women: a prospective cohort study.

Title: Male partner circumcision associated with lower trichomonas vaginalis incidence among pregnant and postpartum kenyan women: a prospective cohort study.
Authors: Pintye, J; Drake, AL; Unger, JA; Matemo, D; Kinuthia, J; McClelland, RS; John-Stewart, G
Publisher Information: University of Nairobi
Publication Year: 2016
Collection: University of Nairobi Digital Repository
Subject Terms: EPIDEMIOLOGY (CLINICAL); PREGNANCY; TRICHOMONAS; WOMEN
Description: OBJECTIVE: Trichomonas vaginalis is the world's most common curable STI and has implications for reproductive health in women. We determined incidence and correlates of T. vaginalis in an HIV-uninfected peripartum cohort. METHODS: Women participating in a prospective study of peripartum HIV acquisition in Western Kenya were enrolled during pregnancy and followed until 9 months post partum. T. vaginalis was assessed every 1-3 months using wet mount microscopy. Correlates of incident T. vaginalis were determined using Cox proportional hazards models. RESULTS: Among 1271 women enrolled, median age was 22 years (IQR 19-27) and gestational age was 22 weeks (IQR 18-26); most (78%) were married and had uncircumcised male partners (69%). Prevalent T. vaginalis was detected in 81 women (6%) at enrolment. Among women without T. vaginalis at enrolment, 112 had T. vaginalis detected during 1079 person-years of follow-up (10.4 per 100 person-years). After adjustment for socio-economic factors, male partner circumcision status, pregnancy status and other STIs, T. vaginalis incidence was higher during pregnancy than post partum (22.3 vs 7.7 per 100 person-years, adjusted HR (aHR) 3.68, 95% CI 1.90 to 7.15, p
Document Type: article in journal/newspaper
Language: English
Relation: https://www.ncbi.nlm.nih.gov/pubmed/27519258; https://hdl.handle.net/11295/100839
Availability: https://hdl.handle.net/11295/100839; https://www.ncbi.nlm.nih.gov/pubmed/27519258
Rights: Attribution-NonCommercial-NoDerivs 3.0 United States ; http://creativecommons.org/licenses/by-nc-nd/3.0/us/
Accession Number: edsbas.D20F4625
Database: BASE