| Title: |
A rational study of the influence of Mn(2+)-insertion in Prussian blue nanoparticles on their photothermal properties |
| Authors: |
Cahu, Maëlle; Ali, Lamiaa Mohamed Ahmed; Sene, Saad; Long, Jérôme; Camerel, Franck; Ciancone, Mathieu; Salles, Fabrice; Chopineau, J.; Devoisselle, Jean-Marie; Félix, Gautier; Cubedo, Nicolas; Rossel, Mireille; Guari, Yannick; Bettache, Nadir; Larionova, Joulia; Gary-Bobo, Magali |
| Contributors: |
Ecole Nationale Supérieure de Chimie de Montpellier (ENSCM); Institut Charles Gerhardt Montpellier - Institut de Chimie Moléculaire et des Matériaux de Montpellier (ICGM); Ecole Nationale Supérieure de Chimie de Montpellier (ENSCM)-Institut de Chimie - CNRS Chimie (INC-CNRS)-Université de Montpellier (UM)-Centre National de la Recherche Scientifique (CNRS); Institut des Biomolécules Max Mousseron Pôle Chimie Balard (IBMM); Institut des Sciences Chimiques de Rennes (ISCR); Université de Rennes (UR)-Institut National des Sciences Appliquées - Rennes (INSA Rennes); Institut National des Sciences Appliquées (INSA)-Institut National des Sciences Appliquées (INSA)-Ecole Nationale Supérieure de Chimie de Rennes (ENSCR)-Institut de Chimie - CNRS Chimie (INC-CNRS)-Centre National de la Recherche Scientifique (CNRS); Mécanismes moléculaires dans les démences neurodégénératives (MMDN); École Pratique des Hautes Études (EPHE); Université Paris Sciences et Lettres (PSL)-Université Paris Sciences et Lettres (PSL)-Institut National de la Santé et de la Recherche Médicale (INSERM)-Université de Montpellier (UM); The authors thank the University of Montpellier and CNRS for financial support, platform MEA of the University of Montpellier and PAC of ICGM for measurements. This work has been supported by ANR with grant number ANR-18-CE09-0012-01. We acknowledge the imaging facility MRI, member of the national infrastructure France-BioImaging supported by the French National Research Agency (ANR-10-INBS-04, «Investments for the future»). F. C. and J. L. thanks Loïc Charbonnière for his helpful discussions on measurements made in D2O.; ANR-18-CE09-0012,NANOBLUE,Nanoparticules de bleu de Prusse pour le théranostic(2018); ANR-10-INBS-0004,France-BioImaging,Développment d'une infrastructure française distribuée coordonnée(2010) |
| Source: |
ISSN: 2050-750X ; Journal of materials chemistry B ; https://hal.science/hal-03414675 ; Journal of materials chemistry B, 2021, 9 (47), pp.9670-9683. ⟨10.1039/d1tb00888a⟩. |
| Publisher Information: |
HAL CCSD; Royal Society of Chemistry |
| Publication Year: |
2021 |
| Collection: |
Université de Rennes 1: Publications scientifiques (HAL) |
| Subject Terms: |
MESH: Animals; MESH: Antineoplastic Agents; MESH: Triple Negative Breast Neoplasms; MESH: Xenograft Model Antitumor Assays; MESH: Zebrafish; MESH: Cell Line; Tumor; MESH: Ferrocyanides; MESH: Humans; MESH: Iron; MESH: Manganese; MESH: Nanoparticles; MESH: Photochemical Processes; MESH: Photothermal Therapy; [CHIM]Chemical Sciences; [PHYS.COND.CM-MS]Physics [physics]/Condensed Matter [cond-mat]/Materials Science [cond-mat.mtrl-sci]; [SDV.IB.BIO]Life Sciences [q-bio]/Bioengineering/Biomaterials |
| Description: |
International audience ; We investigated a series of Mn-Prussian blue (PB) nanoparticles NaMnFe[Fe(CN)]·HO of similar size, surface state and cubic morphology with various amounts of Mn synthesized through a one step self-assembly reaction. We demonstrated by a combined experimental-theoretical approach that during the synthesis, Mn substituted Fe up to a Mn/Na-Mn-Fe ratio of 32 at% in the PB structure, while for higher amounts, the Mn[Fe(CN)] analogue is obtained. For comparison, the post-synthetic insertion of Mn2+ in PB nanoparticles was also investigated and completed with Monte-Carlo simulations to probe the plausible adsorption sites. The photothermal conversion efficiency () of selected samples was determined and showed a clear dependence on the Mnamount with a maximum efficiency for a Mn/Na-Mn-Fe ratio of 10 at% associated with a dependence on the nanoparticle concentration. Evaluation of the photothermal properties of these nanoparticles performed on triple negative human breast adenocarcinoma (MDA-MB-231) cells by using continuous and pulsed laser irradiation confirm their excellent PTT efficiency permitting low dose use. |
| Document Type: |
article in journal/newspaper |
| Language: |
English |
| Relation: |
info:eu-repo/semantics/altIdentifier/pmid/34726228; PUBMED: 34726228; WOS: 000713779500001 |
| DOI: |
10.1039/d1tb00888a |
| Availability: |
https://hal.science/hal-03414675; https://hal.science/hal-03414675v1/document; https://hal.science/hal-03414675v1/file/A%20rational%20study%20of%20the%20influence%20of%20Mn2.pdf; https://doi.org/10.1039/d1tb00888a |
| Rights: |
info:eu-repo/semantics/OpenAccess |
| Accession Number: |
edsbas.D3D5C37C |
| Database: |
BASE |