| Title: |
Methylprednisolone versus intravenous immunoglobulins in children with paediatric inflammatory multisystem syndrome temporally associated with SARS-CoV-2 (PIMS-TS): an open-label, multicentre, randomised trial. |
| Authors: |
Welzel, T; Atkinson, A; Schöbi, N; Andre, MC; Bailey, DGN; Blanchard-Rohner, G; Buettcher, M; Grazioli, S; Koehler, H; Perez, M-H; Trück, J; Vanoni, F; Zimmermann, P; Sanchez, C; Bielicki, JA; Schlapbach, LJ; Swissped RECOVERY Trial Group |
| Publisher Information: |
Elsevier |
| Publication Year: |
2023 |
| Collection: |
St George's University of London: Repository |
| Description: |
BACKGROUND: The emergence of paediatric inflammatory multisystem syndrome temporally associated with SARS-CoV-2 (PIMS-TS) led to the widespread use of anti-inflammatory treatments in the absence of evidence from randomised controlled trials (RCTs). We aimed to assess the effectiveness of intravenous methylprednisolone compared with intravenous immunoglobulins. METHODS: This is an open-label, multicentre, two-arm RCT done at ten hospitals in Switzerland in children younger than 18 years hospitalised with PIMS-TS (defined as age |
| Document Type: |
article in journal/newspaper |
| File Description: |
application/vnd.openxmlformats-officedocument.wordprocessingml.document |
| Language: |
English |
| ISSN: |
2352-4650 |
| Relation: |
https://openaccess.sgul.ac.uk/id/eprint/115175/8/Swissped_manuscript_LCAH_R2_clean.docx; https://openaccess.sgul.ac.uk/id/eprint/115175/6/Swissped_Supplement_LCAH_R2_final.docx; Welzel, T; Atkinson, A; Schöbi, N; Andre, MC; Bailey, DGN; Blanchard-Rohner, G; Buettcher, M; Grazioli, S; Koehler, H; Perez, M-H; et al. Welzel, T; Atkinson, A; Schöbi, N; Andre, MC; Bailey, DGN; Blanchard-Rohner, G; Buettcher, M; Grazioli, S; Koehler, H; Perez, M-H; Trück, J; Vanoni, F; Zimmermann, P; Sanchez, C; Bielicki, JA; Schlapbach, LJ; Swissped RECOVERY Trial Group (2023) Methylprednisolone versus intravenous immunoglobulins in children with paediatric inflammatory multisystem syndrome temporally associated with SARS-CoV-2 (PIMS-TS): an open-label, multicentre, randomised trial. Lancet Child Adolesc Health, 7 (4). pp. 238-248. ISSN 2352-4650 https://doi.org/10.1016/S2352-4642(23)00020-2 SGUL Authors: Bielicki, Julia Anna |
| DOI: |
10.1016/S2352-4642(23)00020-2 |
| Availability: |
https://openaccess.sgul.ac.uk/id/eprint/115175/; https://openaccess.sgul.ac.uk/id/eprint/115175/8/Swissped_manuscript_LCAH_R2_clean.docx; https://openaccess.sgul.ac.uk/id/eprint/115175/6/Swissped_Supplement_LCAH_R2_final.docx; https://doi.org/10.1016/S2352-4642(23)00020-2 |
| Rights: |
cc_by_nc_nd_4 |
| Accession Number: |
edsbas.D413D12E |
| Database: |
BASE |