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DDiT4L promotes autophagy and inhibits pathological cardiac hypertrophy in response to stress

Title: DDiT4L promotes autophagy and inhibits pathological cardiac hypertrophy in response to stress
Authors: Simonson, Bridget; Subramanya, Vinita; Chan, Mun Chun; Zhang, Aifeng; Franchino, Hannabeth; Ottaviano, Filomena; Mishra, Manoj K.; Knight, Ashley C.; Hunt, Danielle; Ghiran, Ionita; Khurana, Tejvir S.; Kontaridis, Maria I.; Rosenzweig, Anthony; Das, Saumya
Contributors: National Heart, Lung, and Blood Institute; Klarman Family Foundation
Source: Science Signaling ; volume 10, issue 468 ; ISSN 1945-0877 1937-9145
Publisher Information: American Association for the Advancement of Science (AAAS)
Publication Year: 2017
Description: The mTORC1 inhibitor DDiT4L prevents the increase in heart size caused by stress.
Document Type: article in journal/newspaper
Language: English
DOI: 10.1126/scisignal.aaf5967
Availability: https://doi.org/10.1126/scisignal.aaf5967; https://www.science.org/doi/pdf/10.1126/scisignal.aaf5967
Rights: http://www.sciencemag.org/about/science-licenses-journal-article-reuse
Accession Number: edsbas.D49BB6D6
Database: BASE