| Title: |
Anticoagulation Practice and Risk of Portal Vein Thrombosis Following Pancreaticoduodenectomy or Total Pancreatectomy with Venous Resection |
| Authors: |
Labib, Peter L.; McKay, Siobhan C.; Perrodin, Stéphanie F.; Bolm, Louisa; Mownah, Omar A.; Bellotti, Ruben; McClements, Jane; Sultana, Asma; Skipworth, James RA.; Balakrishnan, Anita; Durán, Manuel; Moris, Dimitrios; Milburn, James A.; Kurtoğlu, Gökalp K.; Carino, Nicola De'Liguori; Domínguez-Rosado, Ismael; Pandanaboyana, Sanjay; Ghotbi, Jacob; Marchegiani, Giovanni; Athwal, Tejinderjit S.; Stättner, Stefan; Karavias, Dimitrios D.; Al-Sarireh, Bilal; Morris, Paul D.; Connor, Saxon; Halimi, Asif; Leonhardt, Carl-Stephan; Hodgson, Russell; Samra, Jaswinder S.; Mittal, Anubhav; Fisher, Oliver M.; Lim, Christopher SH.; Banting, Simon W.; Koea, Jonathan; Yoshino, Osamu; Silva, Michael A.; Bhogal, Ricky H.; Croagh, Daniel; Cavallucci, David J.; Loveday, Benjamin PT.; Dunne, Declan FJ.; Aroori, Somaiah; Davidson, Brian R.; null, null; Roberts, Keith J. |
| Contributors: |
Labib, Peter L.; Mckay, Siobhan C.; Perrodin, Stéphanie F.; Bolm, Louisa; Mownah, Omar A.; Bellotti, Ruben; Mcclements, Jane; Sultana, Asma; Skipworth, James Ra.; Balakrishnan, Anita; Durán, Manuel; Moris, Dimitrio; Milburn, James A.; Kurtoğlu, Gökalp K.; Carino, Nicola De'Liguori; Domínguez-Rosado, Ismael; Pandanaboyana, Sanjay; Ghotbi, Jacob; Marchegiani, Giovanni; Athwal, Tejinderjit S.; Stättner, Stefan; Karavias, Dimitrios D.; Al-Sarireh, Bilal; Morris, Paul D.; Connor, Saxon; Halimi, Asif; Leonhardt, Carl-Stephan; Hodgson, Russell; Samra, Jaswinder S.; Mittal, Anubhav; Fisher, Oliver M.; Lim, Christopher Sh.; Banting, Simon W.; Koea, Jonathan; Yoshino, Osamu; Silva, Michael A.; Bhogal, Ricky H.; Croagh, Daniel; Cavallucci, David J.; Loveday, Benjamin Pt.; Dunne, Declan Fj.; Aroori, Somaiah; Davidson, Brian R.; Null, Null; Roberts, Keith J. |
| Publication Year: |
2025 |
| Collection: |
Padua Research Archive (IRIS - Università degli Studi di Padova) |
| Subject Terms: |
anticoagulant; pancreatectomy; pancreatic neoplasm; portal vein; survival; venous thrombosis |
| Description: |
Objective: Assess anticoagulation practice and portal vein thrombosis (PVT) risk following pancreaticoduodenectomy (PD) or total pancreatectomy (TP) with venous resection (VR). Background: Retrospective studies suggest an increased risk of PVT following PD/TP with VR. However, anticoagulation practice is variable and its efficacy at preventing PVT is unknown. Methods: This multicentre cohort study (Europe, USA, Mexico, Turkey, Australia, New Zealand) included consecutive patients undergoing PD/TP with VR between 2018-2022. A 1:1 age and sex matched cohort undergoing PD/TP without VR was also collected to assess PVT risk without VR. Results: Among 972 patients who underwent PD/TP with VR, 259 (26.6%) received inpatient therapeutic anticoagulation and 242 (25.0%) were discharged on therapeutic anticoagulation. Thirty-day, 90-day and one-year PVT risk following VR was 5.1%, 7.3%, and 11.6%, versus 1.0%, 1.3% and 2.6% in patients without VR (P |
| Document Type: |
article in journal/newspaper |
| Language: |
English |
| Relation: |
info:eu-repo/semantics/altIdentifier/pmid/40996212; journal:ANNALS OF SURGERY; https://hdl.handle.net/11577/3568384 |
| DOI: |
10.1097/sla.0000000000006954 |
| Availability: |
https://hdl.handle.net/11577/3568384; https://doi.org/10.1097/sla.0000000000006954 |
| Accession Number: |
edsbas.D4D8050B |
| Database: |
BASE |