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The Role of Nutritional Therapy in the Treatment of Adults with Crohn’s Disease: A Review

Title: The Role of Nutritional Therapy in the Treatment of Adults with Crohn’s Disease: A Review
Authors: Raffaele Li Voti; Fabio Salvatore Macaluso; Elena Banci; Angelo Campanozzi; Giulia D’Arcangelo; Alessia De Blasi; Salvatore Oliva; Elena Sofia Pieri; Sara Renzo; Cosimo Ruggiero; Giusy Russo; Luca Scarallo; Paolo Lionetti; Ambrogio Orlando
Source: Nutrients ; Volume 17 ; Issue 20 ; Pages: 3186
Publisher Information: Multidisciplinary Digital Publishing Institute
Publication Year: 2025
Collection: MDPI Open Access Publishing
Subject Terms: adults; Crohn’s disease; Crohn’s disease exclusion diet; Mediterranean diet; nutritional therapy
Subject Geographic: agris
Description: Crohn’s disease (CD) is an immune-mediated inflammatory bowel disease (IBD) with a multifactorial pathogenesis involving genetic predisposition, immune dysregulation, and environmental triggers. Dietary patterns have recently garnered growing attention for their potential benefits and risks in patients with IBD. Nutritional therapy has been established as an effective option in pediatric populations, but its role in adults remains less defined. The available studies indicate that while no single diet can be universally recommended, adherence to a Mediterranean diet is associated with multiple health benefits. Nutritional therapy appears promising in inducing clinical remission in adults with mild to moderate CD, particularly when partial enteral nutrition is combined with food-based modifications. Tailoring these strategies to cultural contexts and providing support from qualified dietitians may improve adherence, clinical outcomes, and overall quality of life. This review highlights the growing role of nutritional therapy in adult CD and its potential integration into routine management alongside conventional treatments.
Document Type: text
File Description: application/pdf
Language: English
Relation: Nutritional Immunology; https://dx.doi.org/10.3390/nu17203186
DOI: 10.3390/nu17203186
Availability: https://doi.org/10.3390/nu17203186
Rights: https://creativecommons.org/licenses/by/4.0/
Accession Number: edsbas.D4EC992D
Database: BASE