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Extragenital Müllerian adenosarcoma with pouch of Douglas location.

Title: Extragenital Müllerian adenosarcoma with pouch of Douglas location.
Authors: PATRELLI TS; SILINI EM; BERRETTA R; FRANCHI L; THAI E; LUKANOVIC A; MODENA AB; GIZZO, SALVATORE; NARDELLI, GIOVANNI BATTISTA
Contributors: Patrelli, T; Silini, Em; Gizzo, Salvatore; Berretta, R; Franchi, L; Thai, E; Lukanovic, A; Nardelli, GIOVANNI BATTISTA; Modena, Ab
Publisher Information: BIOMED CENTRAL LTD, MIDDLESEX HOUSE, 34-42 CLEVELAND ST, LONDON, ENGLAND, W1T 4LB
Publication Year: 2011
Collection: Padua Research Archive (IRIS - Università degli Studi di Padova)
Description: BMC Cancer. 2011 May 15;11:171. Extragenital Müllerian adenosarcoma with pouch of Douglas location. Patrelli TS, Silini EM, Gizzo S, Berretta R, Franchi L, Thai E, Lukanovic A, Nardelli GB, Modena AB. SourceDepartment of Obstetrics, Gynecological and Perinatology Sciences, University of Parma, Italy. titosilvio.patrelli@gmail.com Abstract BACKGROUND: Of all female genital tract tumors, 1-3% are stromal malignancies. In 8-10% of cases, these are represented by Müllerian adenosarcoma an extremely rare tumor characterized by a stromal component of usually low-grade malignancy and by a benign glandular epithelial component. Variant that arises in the pouch of Douglas is scarcely mentioned in the medical literature. CASE PRESENTATION: A 49-year-old para-0 woman, was seen at our OB/GYN-UNIT because she complained vaguely of pelvic pain. She had a mass of undefined nature in the pouch of Douglas. A simple excision of the mass showed low-grade Müllerian adenosarcoma with areas of stromal overgrowth. One and a half year after surgery, at another hospital, a mass was detected in the patient's posterior vaginal fornix and removed surgically. Six months later she came back to our observation with vaginal bleeding and mass in the vaginal fornix. We performed radical surgery. The pathological examination showed recurrent adenosarcoma. Surgical treatment was supplemented by radiation therapy. CONCLUSIONS: The case of Müllerian adenosarcoma reported here is the third known so far in the literature that was located in the pouch of Douglas. To date, only two other such cases have been reported, including one resulting from neoplastic degeneration of an endometriotic cyst.
Document Type: article in journal/newspaper
Language: English
Relation: info:eu-repo/semantics/altIdentifier/pmid/21575150; info:eu-repo/semantics/altIdentifier/wos/WOS:000291675900001; volume:May 15; firstpage:171; lastpage:172; journal:BMC CANCER; https://hdl.handle.net/11577/137502
Availability: https://hdl.handle.net/11577/137502
Accession Number: edsbas.D54B8331
Database: BASE