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Optimal Heart Failure Medical Therapy and Mortality in Survivors of Cardiogenic Shock: Insights From the FRENSHOCK Registry

Title: Optimal Heart Failure Medical Therapy and Mortality in Survivors of Cardiogenic Shock: Insights From the FRENSHOCK Registry
Authors: Matsushita, K. (Kensuke); Delmas, C. (Clément); Marchandot, B. (Benjamin); Roubille, F. (François); Lamblin, N. (Nicolas); Leurent, G. (Guillaume); Levy, B. (Bruno); Elbaz, M. (Meyer); Champion, S. (Sebastien); Lim, P. (Pascal); Schneider, F. (Francis); Khachab, H. (Hadi); Carmona, A. (Adrien); Trimaille, A. (Antonin); Bourenne, J. (Jeremy); Seronde, M. (Marie‐France); Schurtz, G. (Guillaume); Harbaoui, B. (Brahim); Vanzetto, G. (Gerald); Biendel, C. (Caroline); Labbe, V. (Vincent); Combaret, N. (Nicolas); Mansourati, J. (Jacques); Filippi, E. (Emmanuelle); Maizel, J. (Julien); Merdji, H. (Hamid); Lattuca, B. (Benoit); Gerbaud, E. (Edouard); Bonnefoy, E. (Eric); Puymirat, E. (Etienne); Bonello, L. (Laurent); Morel, O. (Olivier)
Publication Year: 2024
Subject Terms: Aucun
Description: Background: The effects of pharmacological therapy on cardiogenic shock (CS) survivors have not been extensively studied. Thus, this study investigated the association between guideline-directed heart failure (HF) medical therapy (GDMT) and one-year survival rate in patients who are post-CS. Methods and results: FRENSHOCK (French Observatory on the Management of Cardiogenic Shock in 2016) registry was a prospective multicenter observational survey, conducted in metropolitan French intensive care units and intensive cardiac care units. Of 772 patients, 535 patients were enrolled in the present analysis following the exclusion of 217 in-hospital deaths and 20 patients with missing medical records. Patients with triple GDMT (beta-blockers, renin-angiotensin system inhibitors, and mineralocorticoid receptor antagonists) at discharge (n=112) were likely to have lower left ventricular ejection fraction on admission and at discharge compared with those without triple GDMT (n=423) (22% versus 28%, P
Document Type: article in journal/newspaper
Language: English
DOI: 10.1161/JAHA.123.030975
Availability: https://www.ahajournals.org/doi/10.1161/JAHA.123.030975
Rights: Paternité - Pas d'utilisation commerciale - Pas de modification [CC] [BY] [NC] [ND] ; info:eu-repo/semantics/openAccess
Accession Number: edsbas.D564AAB0
Database: BASE