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The generation and utilization of a cancer-oriented representation of the human transcriptome by using expressed sequence tags

Title: The generation and utilization of a cancer-oriented representation of the human transcriptome by using expressed sequence tags
Authors: Brentani, H.; Caballero, O. L.; Camargo, A. A.; da Silva, A. M.; da Silva, W. A.; Neto, E. D.; Grivet, M.; Gruber, A.; Guimaraes, PEM; Hide, W.; Iseli, C.; Jongeneel, C. V.; Kelso, J.; Nagai, M. A.; Ojopi, EPB; Osorio, E. C.; Reis, EMR; Riggins, G. J.; Simpson, AJG; de Souza, S.; Stevenson, B. J.; Strausberg, R. L.; Tajara, E. H.; Verjovski-Almeida, S.; Acencion, M. L.; Bengtsono, M. H.; Bettonip, F.; Bodmerq, W. F.; Brionesr, MRS; Camargos, L. P.; Caveneet, W.; Ceruttiu, J. M.; Coelho Andradev, L. E.; Costa dos Santosn, P. C.; Costaw, MCR; da Silvaw, I. T.; Esteciox, MRH; Ferreiraw, K. S.; Furnarit, F. B.; Faria, M.; Galantep, PAF; Guimaraesy, G. S.; Holandaw, A. J.; Kimuraz, E. T.; Leerkesp, M. R.; Xin, L. A.; Macielu, RMB; Martinsbb, EAL; Massirero, K. B.; Melor, ASA; Mestrinercc, C. A.; Miraccan, E. C.; Mirandas, L. L.; Nobregadd, F. G.; Oliveirap, P. S.; Paquolaee, ACM; Pandolficc, JRC; Pardiniff, MIDC; Passettip, F.; Quackenbushgg, J.; Schnabelr, B.; Sogayaro, M. C.; Souzap, J. E.; Valentinicc, SR; Zaiatsp, A. C.; Amaralx, E. J.; Arnaldiu, LAT; de Araujow, A. G.; de Bessan, S. A.; Bicknellq, D. C.; de Camaroy, MER; Carrarop, D. M.; Carrerhh, H.; Carvalhop, A. F.; Colino, C.; Costaii, F.; Curcioz, C.; da Silvaw, IDCG; da Silvav, N. P.; Dellamanop, M.; El-Dorrykk, H.; Espreaficoll, E. M.; Ferreirakk, AJS; Ferreiraw, C. A.; Fortesmm, MAHZ; Gamann, A. H.; Giannella-Netomm, D.; Giannellamm, MLCC; Giorgimm, R. R.; Goldmanoo, G. H.; Goldmanpp, MHS; Hackely, C.; Hobb, P. L.; Kimuraqq, E. M.; Kowalskirr, L. P.; Kriegerss, J. E.; Leitebb, LCC; Lopesrr, A.; Lunamm, AMSC; Mackaytt, A.; Marin, SKN; Marquesw, A. A.; Martinsp, W. K.; Montagninirr, A.; Netorr, M. M.; Nascimentobb, ALTO; Nevilleuu, A. M.; Nobregadd, M. P.; O'Harett, M. J.; Otsukavv, A. Y.; de Melop, AIR; Paco-Larsonww, M. L.; Pereiraii, G. G.; Pereira da Silvav, N.; Pesquerojj, J. B.; Pessoajj, J. G.; Rahal, Paula; Rainhoxx, C. A.; Rodriguesyy, V; Rogatto, Silvia Regina; Romanozz, C. M.; Romeirox, J. G.; Rossirr, B. M.; Rusticcin, M.; de Sayy, R. G.; Sant' Annaqq, S. C.; Sarmazox, M. L.; de Lima e Silvay, T. C.; Soaresrr, F. A.; Sonatiqq, M. D.; Sousall, J. D.; Queirozy, D.; Valenteww, V; Vettorep, A. L.; Villanovavv, F. E.; Zagow, M. A.; Zalcbergp, H.
Contributors: Universidade Estadual Paulista (UNESP)
Publisher Information: Natl Acad Sciences
Publication Year: 2003
Collection: Universidade Estadual Paulista São Paulo: Repositório Institucional UNESP
Description: Whereas genome sequencing defines the genetic potential of an organism, transcript sequencing defines the utilization of this potential and links the genome with most areas of biology. To exploit the information within the human genome in the fight against cancer, we have deposited some two million expressed sequence tags (ESTs) from human tumors and their corresponding normal tissues in the public databases. The data currently define approximate to23,500 genes, of which only approximate to1,250 are still represented only by ESTs. Examination of the EST coverage of known cancer-related (CR) genes reveals that
Document Type: article in journal/newspaper
File Description: 13418-13423
Language: English
ISSN: 0027-8424
Relation: Proceedings of the National Academy of Sciences of the United States of America; 9.504; 6,092; http://dx.doi.org/10.1073/pnas.1233632100; Proceedings of the National Academy of Sciences of the United States of America. Washington: Natl Acad Sciences, v. 100, n. 23, p. 13418-13423, 2003.; http://hdl.handle.net/11449/39236; WOS:000186573700056; 7991082362671212; orcid:0000-0001-5693-6148
DOI: 10.1073/pnas.1233632100
Availability: http://hdl.handle.net/11449/39236; https://doi.org/10.1073/pnas.1233632100
Rights: closedAccess
Accession Number: edsbas.D6589D17
Database: BASE