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Drug use and needle sharing among adolescents and young adults in Nigeria: A cross-sectional secondary analysis of data from a multi-site clinical trial.

Title: Drug use and needle sharing among adolescents and young adults in Nigeria: A cross-sectional secondary analysis of data from a multi-site clinical trial.
Authors: Agunbiade, Simisola; Gbaja-Biamila, Titilola; Oladele, David; Obiezu-Umeh, Chisom; Musa, Adesola Zaidat; Blessing, Lateef Akeem; Tahlil, Kadija Muse; Akinsolu, Folahanmi Tomiwa; Conserve, Donaldson F; Adeoti, Ebenezer; Xian, Hong; Kuriakose, Kevin; Iwelunmor, Juliet; Ezechi, Oliver; Tucker, Joseph
Publisher Information: Elsevier
Publication Year: 2025
Collection: London School of Hygiene & Tropical Medicine: LSHTM Research Online
Description: BACKGROUND: Adolescents and young adults (AYA, 14-24 years old) have the highest rates of drug use in most low- and middle-income countries. Little is known about the drivers of drug use among AYA in Nigeria and harm reduction services are limited. METHODS: A secondary data analysis was performed of the baseline survey of the 'I-TEST' study involving AYA in Nigeria. The two primary outcomes of interest were lifetime measures of drug use and needle sharing. Logistic regression analyses were performed to obtain odds ratios for the associations between socio-demographic exposures and the two primary outcomes. Odds ratios were subsequently adjusted for age and sex. RESULTS: 1500 AYA survey responses were analysed. Respondents were mostly unemployed, students, and living in southern Nigeria. Drug use was reported by 301/1500(20.3 %) AYA. Among these, 213/301(71.5 %) reported needle sharing. Drug use did not vary by age (OR:0.94, 95 %CI:0.73-1.22) or sex (OR:1.00, 95 %CI:0.77-1.28). AYA in the North-Central zone had higher odds of drug use (OR:1.86, 95 %CI:1.28-2.69) and needle sharing (OR:2.51, 95 %CI:1.07-5.91) compared to AYA in the South-West zone of Nigeria. AYA aged 14-19 had higher odds of needle sharing compared to those aged 20-24 (OR:3.49, 95 %CI:1.94-6.26). Female AYA had higher odds of needle sharing compared to males (OR:5.05, 95 %CI:2.85-8.95). CONCLUSIONS: Drug use and needle sharing are common among AYA in Nigeria. There is an urgent need for harm reduction services and research informed by AYA.
Document Type: article in journal/newspaper
File Description: text
Language: English
ISSN: 0376-8716
Relation: https://researchonline.lshtm.ac.uk/id/eprint/4675891/1/Agunbiade-etal-2025-Drug-use-and-needle-sharing-among-adolescents-and-young-adults-in-Nigeria.pdf; Agunbiade, Simisola; Gbaja-Biamila, Titilola; Oladele, David; Obiezu-Umeh, Chisom; Musa, Adesola Zaidat; Blessing, Lateef Akeem; Tahlil, Kadija Muse; Akinsolu, Folahanmi Tomiwa; Conserve, Donaldson F; Adeoti, Ebenezer; +5 more.Xian, Hong; Kuriakose, Kevin; Iwelunmor, Juliet; Ezechi, Oliver; and Tucker, Joseph ORCID logo (2025) Drug use and needle sharing among adolescents and young adults in Nigeria: A cross-sectional secondary analysis of data from a multi-site clinical trial. Drug and alcohol dependence, 271. 112666-. ISSN 0376-8716 DOI:10.1016/j.drugalcdep.2025.112666
DOI: 10.1016/j.drugalcdep.2025.112666
Availability: https://researchonline.lshtm.ac.uk/id/eprint/4675891/; https://doi.org/10.1016/j.drugalcdep.2025.112666
Rights: cc_by_4
Accession Number: edsbas.D6C599E1
Database: BASE