| Title: |
EFFECT OF ANTIHYPERTENSIVE DEPRESCRIBING ON SERIOUS ADVERSE EVENTS, MORTALITY, AND CARDIOVASCULAR DISEASE: LONG-TERM FOLLOW-UP OF THE OPTIMISE RANDOMISED CONTROLLED TRIAL |
| Authors: |
Sheppard, James; Temple, Eleanor; Wang, Ariel; Smith, Anne; Pollock, Stephanie; Ford, Gary; Hobbs, Richard; Kenealy, Nicola; Lown, Mark; De Lusignan, Simon; Mant, Jonathan; Mccartney, David; Payne, Rupert; Williams, Marney; Yu, Ly -Mee; Mcmanus, Richard |
| Source: |
Journal of Hypertension ; volume 42, issue Suppl 1, page e109-e110 ; ISSN 0263-6352 1473-5598 |
| Publisher Information: |
Ovid Technologies (Wolters Kluwer Health) |
| Publication Year: |
2024 |
| Description: |
Objective: Deprescribing of antihypertensive medications is recommended for some older patients with polypharmacy and frailty. The OPTIMISE trial showed that this can be achieved without affecting blood pressure control at 3-month follow-up. This longer-term follow-up study aimed to examine the impact on serious adverse events (SAEs), mortality and cardiovascular disease (CVD) outcomes after at least 3 years. Design and method: Participants aged 80 years or older, with systolic blood pressure |
| Document Type: |
article in journal/newspaper |
| Language: |
English |
| DOI: |
10.1097/01.hjh.0001020408.42462.e5 |
| Availability: |
https://doi.org/10.1097/01.hjh.0001020408.42462.e5; https://journals.lww.com/10.1097/01.hjh.0001020408.42462.e5 |
| Accession Number: |
edsbas.D7A3DC76 |
| Database: |
BASE |