| Title: |
Worldwide trends in population-based survival for children, adolescents, and young adults diagnosed with leukaemia, by subtype, during 2000–14 (CONCORD-3) : analysis of individual data from 258 cancer registries in 61 countries |
| Authors: |
Ssenyonga, Naomi; Stiller, Charles; Nakata, Kayo; Shalkow, Jaime; Redmond, Shelagh; Bulliard, Jean-Luc; Girardi, Fabio; Fowler, Christine; Marcos-Gragera, Rafael; Bonaventure, Audrey; Saint-Jacques, Nathalie; Minicozzi, Pamela; Rodriguez-Barranco, Miguel; Laronningen, Siri; Di Carlo, Veronica; Magi, Margit; Valkov, Mikhail; Seppa, Karri; Wyn Huws, Dyfed; Coleman, Michel P.; Allemani, Claudia; Bouzbid, S.; Hamdi-Chérif, M.; Kara, L.; Meguenni, K.; Regagba, D.; Bayo, S.; Cheick Bougadari, T.; Manraj, S.S.; Bendahhou, K.; Ladipo, A.; Ogunbiyi, O. J.; Somdyala Chaplin, N. I. M.; Moreno, F.; Calabrano, G. H.; Espinola, S. B.; Carballo Quintero, B.; Fita, R.; Laspada, W. D.; Ibañez, S. G.; Lima, C. A.; Mafra Da Costa, A.; De Souza, P. C. F.; Chaves, J.; Laporte, C. A.; Curado, M. P.; de Oliveira, J. C.; Veneziano, C. L. A.; Veneziano, D. B.; Almeida, A. B. M.; Latorre, M. R. D. O.; Rebelo, M. S.; Santos, M. O.; Azevedo e Silva, G.; Galaz, J. C.; Aparicio Aravena, M.; Sanhueza Monsalve, J.; Herrmann, D. A.; Vargas, S.; Herrera, V. M.; Uribe, C. J.; Bravo, L. E.; Garcia, L. S.; Arias-Ortiz, N. E.; Morantes, D.; Jurado, D. M.; Yépez Chamorro, M. C.; Delgado, S.; Ramirez, M.; Galán Alvarez, Y. H.; Torres, P.; Martínez-Reyes, F.; Jaramillo, L.; Quinto, R.; Castillo, J.; Mendoza, M.; Cueva, P.; Yépez, J. G.; Bhakkan, B.; Deloumeaux, J.; Joachim, C.; Macni, J.; Carrillo, R.; Shalkow Klincovstein, J.; Rivera Gomez, R.; Perez, P.; Poquioma, E.; Tortolero-Luna, G.; Zavala, D.; Alonso, R.; Barrios, E.; Eckstrand, A.; Nikiforuk, C.; Woods, R. R.; Noonan, G.; Turner, D.; Kumar, E.; Zhang, B.; Dowden, J. J.; Doyle, G. P.; Saint-Jacques, N.; Walsh, G.; Anam, A.; De, P.; McClure, C. A.; Vriends, K. A.; Bertrand, C.; Ramanakumar, A. V.; Kozie, S.; Stuart-Panko, H.; Freeman, T.; George, J. T.; Avila, R. M.; O’Brien, D. K.; Holt, A.; Almon, L.; Kwong, S.; Morris, C.; Rycroft, R.; Mueller, L.; Phillips, C. E.; Brown, H.; Cromartie, B.; Ruterbusch, J.; Schwartz, A. G.; Levin, G. M.; Wohler, B.; Bayakly, R.; Ward, K. C.; Gomez, S. L.; McKinley, M.; Cress, R.; Davis, J.; Hernandez, B.; Johnson, C. J.; Morawski, B. M.; Ruppert, L. P.; Bentler, S.; Charlton, M. E.; Huang, B; TC Tucker D, T. C.; Deapen, D.; Liu, L.; Hsieh, M. C.; Wu, X. C.; Schwenn, M.; K Stern ST, K.; Gershman, S. T.; Knowlton, R. C.; Alverson, G.; Weaver, T.; Desai, J.; Rogers, D. B.; Jackson-Thompson, J.; Lemons, D.; Zimmerman, H. J.; Hood, M.; Roberts-Johnson, J.; Hammond, W.; Rees, J. R.; Pawlish, K. S.; Stroup, A.; Key, C.; Wiggins, C.; Kahn, A. R.; Schymura, M. J.; Radhakrishnan, S.; Rao, C.; Giljahn, L. K.; Slocumb, R. M.; Dabbs, C.; Espinoza, R. E.; Aird, K. G.; Beran, T.; Rubertone, J. J.; Slack, S. J.; Oh, J.; Janes, T. A.; Schwartz, S. M.; Chiodini, S. C.; Hurley, D. M.; Whiteside, M. A.; Rai, S.; Williams, M. A.; Herget, K.; Sweeney, C.; Johnson, A. T.; Keitheri Cheteri, M. B.; Migliore Santiago, P.; Blankenship, S. E.; Farley, S.; Borchers, R.; Malicki, R.; Espinoza, J.; Grandpre, J.; Weir, H. K.; Wilson, R.; Edwards, B. K.; Mariotto, A.; Wang, N.; Yang, L.; Chen, J. S.; Zhou, Y.; He, Y. T.; Song, G. H.; Gu, X. P.; Mei, D.; Mu, H. J.; Ge, H. M.; Wu, T. H.; Li, Y. Y.; Zhao, D. L.; Jin, F.; Zhang, J. H.; Zhu, F. D.; Junhua, Q.; Yang, Y. L.; Jiang, C. X.; Biao, W.; Wang, J.; Li, Q. L.; Yi, H.; Zhou, X.; Dong, J.; Li, W.; Fu, F. X.; Liu, S. Z.; Chen, J. G.; Zhu, J.; Li, Y. H.; Lu, Y. Q.; Fan, M.; Huang, S. Q.; Guo, G. P.; Zhaolai, H.; Wei, K.; Chen, W. Q.; Wei, W.; Zeng, H.; Demetriou, A. V.; Mang, W. K.; Ngan, K. C.; Kataki, A. C.; Krishnatreya, M.; Jayalekshmi, P. A.; Sebastian, P.; George, P. S.; Mathew, A.; Nandakumar, A.; Malekzadeh, R.; Roshandel, G.; Keinan-Boker, L.; Silverman, B. G.; Ito, H.; Koyanagi, Y.; Sato, M.; Tobori, F.; Nakata, I.; Teramoto, N.; Hattori, M.; Kaizaki, Y.; Moki, F.; Sugiyama, H.; Utada, M.; Nishimura, M.; Yoshida, K.; Kurosawa, K.; Nemoto, Y.; Narimatsu, H.; Sakaguchi, M.; Kanemura, S.; Naito, M.; Narisawa, R.; Miyashiro, I.; Nakata, K.; Mori, D.; Yoshitake, M.; Oki, I.; Fukushima, N.; Shibata, A.; Iwasa, K.; C Ono T O KW, C.; Matsuda, T.; Nimri, O.; Jung, K. W.; Won, Y. J.; Alawadhi, E.; Elbasmi, A.; Manan, A. Ab.; Adam, F.; Nansalmaa, E.; Tudev, U.; Ochir, C.; Khater, AM AI; Mistiri, MM EI; Lim, G. H.; Teo, Y. Y.; Chiang, C. J.; Lee, W. C.; Buasom, R.; Sangrajrang, S.; Suwanrungruang, K.; Vatanasapt, P.; Daoprasert, K.; Pongnikorn, D.; Leklob, A.; Sangkitipaiboon, S.; Geater, S. L.; Sriplung, H.; Ceylan, O.; Kög, I.; Dirican, O.; Köse, T.; Gurbuz, T.; Karaşahin, F. E.; Turhan, D.; Aktaş, U.; Halat, Y.; Eser, S.; Yakut, C. I.; Altinisik, M.; Cavusoglu, Y.; Türkköylü, A.; Üçüncü, N.; Hackl, M.; Zborovskaya, A. A.; Aleinikova, O. V.; Henau, K.; Van Eycken, L.; Atanasov, T. Y.; Valerianova, Z.; Šekerija, M.; Dušek, L.; Zvolský, M.; Steinrud Mørch, L.; Storm, H.; Wessel Skovlund, C.; Innos, K.; Mägi, M.; Malila, N.; Seppä, K.; Jégu, J.; Velten, M.; Cornet, E.; Troussard, X.; Bouvier, A. M.; Guizard, A. V.; Bouvier, V.; Launoy, G.; Dabakuyo Yonli, S.; Poillot, M. L.; Maynadié, M.; Mounier, M.; Vaconnet, L.; Woronoff, A. S.; Daoulas, M.; Robaszkiewicz, M.; Clavel, J.; Poulalhon, C.; Desandes, E.; Lacour, B.; Baldi, I.; Pouchieu, C.; Amadeo, B.; Coureau, G.; Monnereau, A.; Orazio, S.; Audoin, M.; D’Almeida, T. C.; Boyer, S.; Hammas, K.; Trétarre, B.; Colonna, M.; Delafosse, P.; Plouvier, S.; Cowppli-Bony, A.; Molinié, F.; Bara, S.; Ganry, O.; Lapôtre-Ledoux, B.; Daubisse-Marliac, L.; Bossard, L. N.; Uhry, Z.; Estève, J.; Stabenow, R.; Wilsdorf-Köhler, H.; Eberle, A.; Luttmann, S.; Löhden, I.; Nennecke, A. L.; Kieschke, J.; Sirri, E.; Justenhoven, C.; Zeissig, S. R.; Holleczek, B.; Eisemann, N.; Katalinic, A.; Asquez, R. A.; Kumar, V.; Petridou, E.; Ólafsdóttir, E. J.; Tryggvadóttir, L.; Murray, D. E.; Walsh, P. M.; Sundseth, H.; Mazzoleni, G.; Vittadello, F.; Coviello, E.; Cuccaro, F.; Galasso, R.; Sampietro, G.; Giacomin, A.; Magoni, M.; Ardizzone, A.; D’Argenzio, A.; Di Prima, A. A.; Ippolito, A.; Lavecchia, A. M.; Sutera Sardo, A.; Gola, G.; Ballotari, P.; Giacomazzi, E.; Ferretti, S.; Dal Maso, L.; Serraino, D.; Celesia, M. V.; Filiberti, R. A.; Pannozzo, F.; Melcarne, A.; Quarta, F.; Andreano, A.; Russo, A. G.; Carrozzi, G.; Cirilli, C.; Cavalieri d’Oro, L.; Rognoni, M.; Fusco, M.; Vitale, M. F.; Usala, M.; Cusimano, R.; Mazzucco, W.; Michiara, M.; Sgargi, P.; Boschetti, L.; Chiaranda, G.; Seghini, P.; Maule, M. M.; Merletti, F.; Spata, E.; Tumino, R.; Mancuso, P.; Falcini, F.; Giorgetti, S.; Caiazzo, A. L.; Cavallo, R.; Piras, D.; Bella, F.; Madeddu, A.; Fanetti, A. C.; Maspero, S.; Carone, S.; Mincuzzi, A.; Candela, G.; Scuderi, T.; Gentilini, M. A.; Rizzello, R.; Rosso, S.; Caldarella, A.; Intrieri, T.; Bianconi, F.; Contiero, P.; Tagliabue, G.; Rugge, M.; Zorzi, M.; Beggiato, S.; Brustolin, A.; Gatta, G.; De Angelis, R.; Vicentini, M.; Zanetti, R.; Stracci, F.; Maurina, A.; Oniščuka, M.; Mousavi, M.; Lipunova, N.; Vincerževskienė, I.; Agius, D.; Calleja, Neville; Siesling, S.; Visser, O.; Johannesen, T. B.; Larønningen, S.; Trojanowski, M.; Macek, P.; Mierzwa, T.; Rachtan, J.; Rosińska, A.; Kępska, K.; Kościańska, B.; Barna, K.; Sulkowska, U.; Gebauer, T.; Łapińska, J. B.; WójcikTomaszewska, J.; Motnyk, M.; Patro, A.; Gos, K.; Sikorska, K.; Bielska-Lasota, M.; Didkowska, J. A.; Wojciechowska, U.; Forjaz de Lacerda, G.; Rego, R. A.; Carrito, B.; Pais, A.; Bento, M. J.; Rodrigues, J.; Lourenço, A.; Mayer-da-Silva, A.; Blaga, L. M.; Coza, D.; Valkov, M. Y.; Gusenkova, L.; Lazarevich, O.; Prudnikova, O.; Vjushkov, D. M.; Egorova, A.; Orlov, A.; Pikalova, L. V.; Zhuikova, L. D.; Adamcik, J.; Safaei Diba, C.; Zadnik, V.; Žagar, T.; De-La-Cruz, M.; Lopez-de-Munain, A.; Aleman, A.; Rojas, D.; Chillarón, R. J.; Navarro, A. I. M.; Marcos-Gragera, R.; Puigdemont, M.; Rodríguez-Barranco, M.; Sánchez Perez, M. J.; Franch Sureda, P.; Ramos Montserrat, M.; Chirlaque López, M. D.; Sánchez Gil, A.; Ardanaz, E.; Guevara, M.; Cañete-Nieto, A.; Peris-Bonet, R.; Carulla, M.; Galceran, J.; Almela, F.; Sabater, C.; Khan, S.; Pettersson, D.; Dickman, P.; Staehelin, K.; Struchen, B.; Herrmann, C.; Egger Hayoz, C.; Bouchardy, C.; Schaffar, R.; Went, P.; Mousavi, S. M.; Bulliard, J. L.; Maspoli-Conconi, M.; Kuehni, C. E.; Redmond, S. M.; Bordoni, A.; Ortelli, L.; Chiolero, A.; Konzelmann, I.; Rohrmann, S.; Wanner, M.; Broggio, J.; Rashbass, J.; Stiller, C.; Fitzpatrick, D.; Gavin, A.; Morrison, D. S.; Thomson, C. S.; Greene, G.; Huws, D. W.; Allemani, C.; Coleman, M. P.; Di Carlo, V.; Girardi, F.; Matz, M.; Minicozzi, P.; Sanz, N.; Ssenyonga, N.; Stephens, R.; Chalker, E.; Smith, M.; Gugusheff, J.; You, H.; Qin Li, S.; Dugdale, S.; Moore, J.; Philpot, S.; Pfeiffer, R.; Thomas, H.; Silva Ragaini, B.; Venn, A. J.; Evans, S. M.; Te Marvelde, L.; Savietto, V.; Trevithick, R.; Currow, D.; Fowler, C.; Lewis, C.; CONCORD Working Group |
| Contributors: |
CONCORD Working Group |
| Publisher Information: |
The Lancet Publishing Group |
| Publication Year: |
2022 |
| Collection: |
University of Malta: OAR@UM / L-Università ta' Malta |
| Subject Terms: |
Leukemia; Cancer in children; Cancer in adolescence; Leukemia in children |
| Description: |
Background Leukaemias comprise a heterogenous group of haematological malignancies. In CONCORD-3, we analysed data for children (aged 0–14 years) and adults (aged 15–99 years) diagnosed with a haematological malignancy during 2000–14 in 61 countries. Here, we aimed to examine worldwide trends in survival from leukaemia, by age and morphology, in young patients (aged 0–24 years). Methods We analysed data from 258 population-based cancer registries in 61 countries participating in CONCORD-3 that submitted data on patients diagnosed with leukaemia. We grouped patients by age as children (0–14 years), adolescents (15–19 years), and young adults (20–24 years). We categorised leukaemia subtypes according to the International Classification of Childhood Cancer (ICCC-3), updated with International Classification of Diseases for Oncology, third edition (ICD-O-3) codes. We estimated 5-year net survival by age and morphology, with 95% CIs, using the non-parametric Pohar-Perme estimator. To control for background mortality, we used life tables by country or region, single year of age, single calendar year and sex, and, where possible, by race or ethnicity. All-age survival estimates were standardised to the marginal distribution of young people with leukaemia included in the analysis. Findings 164563 young people were included in this analysis: 121328 (73·7%) children, 22963 (14·0%) adolescents, and 20272 (12·3%) young adults. In 2010–14, the most common subtypes were lymphoid leukaemia (28205 [68·2%] patients) and acute myeloid leukaemia (7863 [19·0%] patients). Age-standardised 5-year net survival in children, adolescents, and young adults for all leukaemias combined during 2010–14 varied widely, ranging from 46% in Mexico to more than 85% in Canada, Cyprus, Belgium, Denmark, Finland, and Australia. Individuals with lymphoid leukaemia had better age-standardised survival (from 43% in Ecuador to ≥80% in parts of Europe, North America, Oceania, and Asia) than those with acute myeloid leukaemia (from 32% in Peru to ≥70% in ... |
| Document Type: |
article in journal/newspaper |
| Language: |
English |
| Relation: |
https://www.um.edu.mt/library/oar/handle/123456789/115306 |
| Availability: |
https://www.um.edu.mt/library/oar/handle/123456789/115306 |
| Rights: |
info:eu-repo/semantics/openAccess ; The copyright of this work belongs to the author(s)/publisher. The rights of this work are as defined by the appropriate Copyright Legislation or as modified by any successive legislation. Users may access this work and can make use of the information contained in accordance with the Copyright Legislation provided that the author must be properly acknowledged. Further distribution or reproduction in any format is prohibited without the prior permission of the copyright holder. |
| Accession Number: |
edsbas.D83888BE |
| Database: |
BASE |