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Spontaneous Non-Aneurysmal Convexity Subarachnoid Hemorrhage: A Scoping Review of Different Etiologies beyond Cerebral Amyloid Angiopathy

Title: Spontaneous Non-Aneurysmal Convexity Subarachnoid Hemorrhage: A Scoping Review of Different Etiologies beyond Cerebral Amyloid Angiopathy
Authors: Zedde M.; Grisendi I.; Assenza F.; Napoli M.; Moratti C.; Pavone C.; Bonacini L.; Cecco G. D.; D'Aniello S.; Pezzella F. R.; Merlino G.; Piazza F.; Pezzini A.; Morotti A.; Fainardi E.; Toni D.; Valzania F.; Pascarella R.
Contributors: Zedde, M; Grisendi, I; Assenza, F; Napoli, M; Moratti, C; Pavone, C; Bonacini, L; Cecco, G; D'Aniello, S; Pezzella, F; Merlino, G; Piazza, F; Pezzini, A; Morotti, A; Fainardi, E; Toni, D; Valzania, F; Pascarella, R
Publisher Information: MDPI; CH
Publication Year: 2024
Collection: Università degli Studi di Milano-Bicocca: BOA (Bicocca Open Archive)
Subject Terms: CAA-related inflammation; cerebral amyloid angiopathy; cerebral venous thrombosi; convexity subarachnoid hemorrhage; endocarditi; intracranial stenosi; MRI; PRES; RCVS; Settore MEDS-26/A - Scienze tecniche di medicina di laboratorio; Settore MEDS-26/B - Scienze delle professioni sanitarie tecniche diagnostiche; assistenziali e della prevenzione; Settore MEDS-26/C - Scienze delle professioni sanitarie della riabilitazione; Settore MEDS-26/D - Scienze tecniche mediche e chirurgiche avanzate
Description: Spontaneous convexity subarachnoid hemorrhage (cSAH) is a vascular disease different from aneurysmal SAH in neuroimaging pattern, causes, and prognosis. Several causes might be considered in individual patients, with a limited value of the patient’s age for discriminating among these causes. Cerebral amyloid angiopathy (CAA) is the most prevalent cause in people > 60 years, but reversible cerebral vasoconstriction syndrome (RCVS) has to be considered in young people. CAA gained attention in the last years, but the most known manifestation of cSAH in this context is constituted by transient focal neurological episodes (TFNEs). CAA might have an inflammatory side (CAA-related inflammation), whose diagnosis is relevant due to the efficacy of immunosuppression in resolving essudation. Other causes are hemodynamic stenosis or occlusion in extracranial and intracranial arteries, infective endocarditis (with or without intracranial infectious aneurysms), primary central nervous system angiitis, cerebral venous thrombosis, and rarer diseases. The diagnostic work-up is fundamental for an etiological diagnosis and includes neuroimaging techniques, nuclear medicine techniques, and lumbar puncture. The correct diagnosis is the first step for choosing the most effective and appropriate treatment.
Document Type: article in journal/newspaper
File Description: ELETTRONICO
Language: English
Relation: info:eu-repo/semantics/altIdentifier/pmid/39124649; info:eu-repo/semantics/altIdentifier/wos/WOS:001287900000001; volume:13; issue:15; journal:JOURNAL OF CLINICAL MEDICINE; https://hdl.handle.net/10281/502840
DOI: 10.3390/jcm13154382
Availability: https://hdl.handle.net/10281/502840; https://doi.org/10.3390/jcm13154382
Rights: info:eu-repo/semantics/openAccess ; license:Creative Commons ; license uri:http://creativecommons.org/licenses/by/4.0/
Accession Number: edsbas.D8615F7B
Database: BASE