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Contact allergy to topical corticosteroids - results from the IVDK and epidemiological risk assessment

Title: Contact allergy to topical corticosteroids - results from the IVDK and epidemiological risk assessment
Authors: Uter, Wolfgang; de Padua, Cristiane Menezes; Pfahlberg, Annette; Nink, Katrin; Schnuch, Axel; Lessmann, Holger
Contributors: Uter, Wolfgang; de Padua, Cristiane Menezes; Pfahlberg, Annette; Nink, Katrin; Schnuch, Axel; Lessmann, Holger
Publisher Information: Wiley-blackwell Publishing, Inc
Publication Year: 2009
Collection: Georg-August-Universität Göttingen: GoeScholar
Description: Background: Contact allergy (CA) to topical corticosteroids (CS) is relatively rare; however, current data from Germany are not available. Furthermore, valid risk assessment needs to take into account of the actual exposure to CS in the population. Patients and Methods: The reaction profile of 9 CS included in a "CS test battery" of the German Contact Dermatitis Research Group (DKG) in patients seen in German clinics belonging to the Information Network of Departments of Dermatology (IVDK; www.ivdk.org) between 01/1995 and 12/2004 was analyzed. Applying the "Clinical Epidemiology/Drug Utilization Research" approach, annual incidences of CA to CS in Germany were extrapolated. These estimates were used as numerator for a relative incidence (RI) estimate which used exposure in terms of "defined daily doses" (DDD) to the respective CS as denominator, the latter information collected by the AOK Research Institute (WIdO). Results: On average, 7.4% of all patients were patch tested with the CS series, mostly yielding
Document Type: article in journal/newspaper
Language: unknown
Relation: 000261976900006
Availability: https://resolver.sub.uni-goettingen.de/purl?gro-2/17893
Rights: info:eu-repo/semantics/openAccess
Accession Number: edsbas.D8E45F12
Database: BASE