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Peri-transplant management of nonalcoholic fatty liver disease in liver transplant candidates

Title: Peri-transplant management of nonalcoholic fatty liver disease in liver transplant candidates
Authors: Samji, N. S.; Heda, R.; Satapathy, S. K.
Source: Journal Articles
Publisher Information: Donald and Barbara Zucker School of Medicine Academic Works
Publication Year: 2020
Collection: Hofstra Northwell Academic Works (Hofstra Northwell School of Medicine)
Subject Terms: Hepatology
Description: © Translational Gastroenterology and Hepatology. All rights reserved. The incidence of non-alcoholic fatty liver disease (NAFLD) is rapidly growing, affecting 25% of the world population. Non-alcoholic steatohepatitis (NASH) is the most severe form of NAFLD and affects 1.5% to 6.5% of the world population. Its rising incidence will make end-stage liver disease (ESLD) due to NASH the number one indication for liver transplantation (LT) in the next 10 to 20 years, overtaking Hepatitis C. Patients with NASH also have a high prevalence of associated comorbidities such as type 2 diabetes, obesity, metabolic syndrome, cardiovascular disease, and chronic kidney disease (CKD), which must be adequately managed during the peritransplant period for optimal post-transplant outcomes. The focus of this review article is to provide a comprehensive overview of the unique challenges these patients present in the peritransplant period, which comprises the pre-transplant, intraoperative, and immediate postoperative periods.
Document Type: text
File Description: application/pdf
Language: unknown
Relation: https://academicworks.medicine.hofstra.edu/publications/6265; https://academicworks.medicine.hofstra.edu/context/publications/article/7266/viewcontent/TranslGastroenterolHepatol2020v5p10.pdf
DOI: 10.21037/TGH.2019.09.09
Availability: https://academicworks.medicine.hofstra.edu/publications/6265; https://academicworks.medicine.hofstra.edu/context/publications/article/7266/viewcontent/TranslGastroenterolHepatol2020v5p10.pdf
Accession Number: edsbas.DA88ED67
Database: BASE