| Title: |
Compassionate mind training for people with Parkinson's disease: A pilot study and predictors of response. |
| Authors: |
Morte, SD; Berti, E; Lalli, C; Modugno, N; Morgante, F; Schrag, A; Makovac, E; Ricciardi, L |
| Publisher Information: |
Wiley |
| Publication Year: |
2024 |
| Collection: |
St George's University of London: Repository |
| Description: |
INTRODUCTION: People with Parkinson's disease (PD) often present with disabling neuropsychiatric symptoms. Compassionate mind training (CMT) is a psychological approach effective in reducing stress and promoting psychological well-being. Heart rate variability (HRV), a measure reflecting sympathovagal balance, has been associated with psychological well-being and a compassionate attitude. AIM: To assess the feasibility and effectiveness of CMT in enhancing the quality of life and psychological well-being in PD patients. Additionally, we evaluated HRV as a physiomarker for assessing the CMT outcomes. METHODS: Twenty-four PD patients participated in the study. A 6-week online CMT intervention was delivered on a weekly basis. At baseline and post-intervention patients completed questionnaires assessing depression, anxiety and quality of life. In a subsample of 11 patients, HRV was measured at baseline and post-intervention in three conditions: at rest, during stress and after 3 min of deep breathing. RESULTS: The attendance rate was 94.3%. Quality of life and perceived stigma improved post-intervention as compared with baseline (p = 0.02 and p = 0.03 for PD Questionnaire-39 total score and Stigma subscore, respectively). After CMT, patients presented better physiological regulation to stress, as measured by higher HRV as compared with baseline (p = 0.005). Notably, patients who were more resilient to stress at baseline (less decrease in HRV during stress) experienced a more substantial reduction in anxiety and depression following CMT. CONCLUSIONS: CMT is feasible and can improve quality of life and stigma in PD patients. HRV emerges as a promising physiomarker for predicting and measuring the outcomes of psychological interventions in PD. |
| Document Type: |
article in journal/newspaper |
| File Description: |
application/pdf; application/vnd.openxmlformats-officedocument.wordprocessingml.document; image/jpeg |
| Language: |
English |
| ISSN: |
1468-1331 |
| Relation: |
https://openaccess.sgul.ac.uk/id/eprint/116361/1/Euro%20J%20of%20Neurology%20-%202024%20-%20Morte%20-%20Compassionate%20mind%20training%20for%20people%20with%20Parkinson%20s%20disease%20%20A%20pilot%20study%20and.pdf; https://openaccess.sgul.ac.uk/id/eprint/116361/6/ene16286-sup-0001-datas1.docx; https://openaccess.sgul.ac.uk/id/eprint/116361/8/ene16286-sup-0002-figures1.jpeg; Morte, SD; Berti, E; Lalli, C; Modugno, N; Morgante, F; Schrag, A; Makovac, E; Ricciardi, L (2024) Compassionate mind training for people with Parkinson's disease: A pilot study and predictors of response. Eur J Neurol, 31 (7). e16286. ISSN 1468-1331 https://doi.org/10.1111/ene.16286 SGUL Authors: Morgante, Francesca |
| DOI: |
10.1111/ene.16286 |
| Availability: |
https://openaccess.sgul.ac.uk/id/eprint/116361/; https://doi.org/10.1111/ene.16286 |
| Rights: |
cc_by_nc_nd_4 |
| Accession Number: |
edsbas.DB545FF6 |
| Database: |
BASE |
