| Title: |
Endometrial Cancer Surgery With or Without Concomitant Stress Urinary Incontinence Surgery |
| Authors: |
Robison, Katina; Wohlrab, Kyle; Howe, Chanelle J.; Richter, Holly E.; Sung, Vivian; Bevis, Kerri S.; Luis, Christine; McCourt, Carolyn; Lowder, Jerry; Occhino, John; Glaser, Gretchen; Lokich, Elizabeth; Dunivan, Gena; Brown, Amy; Tunitsky-Bitton, Elena; Wethington, Stephanie; Chen, Chi Chiung Grace; Rahn, David; Carlson, Matthew; Cram, Robin; Raker, Christina; Clark, Melissa A. |
| Source: |
Obstetrics & Gynecology ; volume 141, issue 4, page 642-652 ; ISSN 0029-7844 |
| Publisher Information: |
Ovid Technologies (Wolters Kluwer Health) |
| Publication Year: |
2023 |
| Description: |
OBJECTIVE: To compare quality of life (QOL) among patients with endometrial intraepithelial neoplasia or early-stage endometrial cancer and stress urinary incontinence (SUI) who chose to have concomitant surgery with cancer surgery alone. METHODS: A multicenter, prospective cohort study was conducted across eight U.S. sites. Potentially eligible patients were screened for SUI symptoms. Those who screened positive were offered referral to urogynecology and incontinence treatment, including concomitant surgery. Participants were categorized into two groups: 1) concomitant cancer and SUI surgery or 2) cancer surgery alone. The primary outcome was cancer-related QOL as measured by the FACT-En (Functional Assessment of Cancer Therapy–Endometrial) (range 0–100; higher score indicates better QOL). The FACT-En and questionnaires assessing urinary symptom–specific severity and effects were assessed before surgery and 6 weeks, 6 months, and 12 months after surgery. Adjusted median regression accounting for clustering was used to examine the relationship between SUI treatment group and FACT-En scores. RESULTS: Of 1,322 (53.1%) patients, 702 screened positive for SUI with 532 analyzed; 110 (21%) chose concomitant cancer and SUI surgery, and 422 (79%) chose cancer surgery alone. FACT-En scores increased for both the concomitant SUI surgery and cancer surgery–only groups from the preoperative to the postoperative period. After adjustment for timepoint and preoperative covariates, the median change in FACT-En score (postoperative−preoperative) was 1.2 points higher (95% CI −1.3 to 3.6) for the concomitant SUI surgery group compared with the cancer surgery–only group across the postoperative period. Median time until surgery (22 days vs 16 days; P |
| Document Type: |
article in journal/newspaper |
| Language: |
English |
| DOI: |
10.1097/aog.0000000000005059 |
| DOI: |
10.1097/AOG.0000000000005059 |
| Availability: |
https://doi.org/10.1097/aog.0000000000005059; https://journals.lww.com/10.1097/AOG.0000000000005059 |
| Accession Number: |
edsbas.DBFA6989 |
| Database: |
BASE |