| Description: |
Introduction: Colitis is a chronic inflammatory bowel disorder with recurrent symptoms, significant morbidity, and limited long-term outcomes with standard pharmacologic treatments. Ad-verse effects, relapse risk, and variable efficacy have prompted interest in integrative approaches that combine Ayurveda, naturopathy, and yoga as complementary strategies for disease management. Materials and Methods: A single-center, cross-sectional observational study was conducted at Patan-jali Wellness, India, involving 41 patients clinically diagnosed with colitis. The integrative interven-tion included personalized Ayurvedic formulations, naturopathic detox therapies, Pitta-pacifying di-ets, and structured yoga practices over a 90-day period. Symptom severity and gastrointestinal quality of life (GI-QoL) were assessed using validated tools at baseline, day 30, day 60, and day 90. Statistical significance was evaluated using repeated measures ANOVA. Results: Mean clinical symptom scores decreased from 516.1 ± 39.71 at baseline to 486.1 ± 37.53 (day 30), 470.63 ± 37.72 (day 60), and 464.51 ± 36.58 (day 90), with a highly significant reduction (p < 0.0001). No adverse events, allergic reactions, or dropouts were reported, indicating high treat-ment safety and feasibility. Discussion: The integrative model combining Ayurvedic, naturopathic, and yogic interventions demonstrated significant improvements in clinical symptomatology and quality of life. The findings supported the potential role of integrative therapies in colitis care; however, the observational design limited causal inference. There is a pressing need for well-designed randomized controlled trials (RCTs) to validate efficacy, refine treatment components, and support broader clinical integration. Conclusion: The integrative approach appeared safe, feasible, and clinically beneficial for patients with colitis. However, future large-scale RCTs are essential to confirm these findings and develop evidence-based integrative treatment protocols. |