| Title: |
Maternal tobacco smoking during pregnancy and children’s emotional and behavioural trajectories : The EDEN mother-child birth cohort study |
| Authors: |
Bonello, Kim; Gomajee, Ramchandar; Ibanez, Gladys; Martins, Silvia; Keyes, Katherine; Nakamura, Aurélie; Lepeule, Johanna; Strandberg- Larsen, Katrine; Fekom, Mathilde; Melchior, Maria |
| Contributors: |
Institut Pierre Louis d'Epidémiologie et de Santé Publique (iPLESP); Institut National de la Santé et de la Recherche Médicale (INSERM)-Sorbonne Université (SU); Sorbonne Université - Département de médecine générale; Sorbonne Université (SU); Columbia Mailman School of Public Health; Columbia University New York; Institute for Advanced Biosciences / Institut pour l'Avancée des Biosciences (Grenoble) (IAB); Établissement Français du Sang Auvergne-Rhône-Alpes Lyon (EFS Auvergne-Rhône-Alpes - Lyon); Établissement Français du Sang La Plaine Saint-Denis (EFS)-Établissement Français du Sang La Plaine Saint-Denis (EFS)-CHU de Grenoble-Alpes - Centre Hospitalier Universitaire CHU Grenoble (CHUGA)-Institut National de la Santé et de la Recherche Médicale (INSERM)-Centre National de la Recherche Scientifique (CNRS)-Université Grenoble Alpes (UGA); Københavns Universitet = University of Copenhagen = Université de Copenhague (UCPH); Equipe de Recherche en Epidémiologie Sociale iPLesp (ERES); Institut National de la Santé et de la Recherche Médicale (INSERM)-Sorbonne Université (SU)-Institut National de la Santé et de la Recherche Médicale (INSERM)-Sorbonne Université (SU) |
| Source: |
ISSN: 1462-2203. |
| Publisher Information: |
CCSD; Oxford University Press (OUP) |
| Publication Year: |
2023 |
| Collection: |
Inserm: HAL (Institut national de la santé et de la recherche médicale) |
| Subject Terms: |
smoking; Pregnancy; Behavior; ADHD; Cohort study; Offspring; [SDV.MHEP.PED]Life Sciences [q-bio]/Human health and pathology/Pediatrics; [SDV.MHEP.PSM]Life Sciences [q-bio]/Human health and pathology/Psychiatrics and mental health; [SDV.SPEE]Life Sciences [q-bio]/Santé publique et épidémiologie |
| Description: |
International audience ; Introduction: The nature of the relationship between maternal tobacco smoking during pregnancy and the occurrence of children’s behavioural problems is still a matter of controversy. We tested this association using data collected among a sample of pregnant women and their offspring followed from birth to early adolescence (age 12 years), accounting for multiple parent, child, and family characteristics.Methods : Data come from 1424 mother-child pairs participating in the EDEN mother-child cohort in France. Using repeated measures (3, 5.5, 8 and 11.5 years) of the mother-reported Strengths and Difficulties Questionnaire, we estimated trajectories of children’s emotional and behavioural difficulties. Two aspects of maternal smoking were studied: the timing (non-smoker, smoking during the periconceptional period or throughout pregnancy) and the level of use (cigarettes/day) during the first trimester of pregnancy. Robust Poisson regression models controlled for confounding factors including maternal mental health and socioeconomic characteristics using propensity scores with the overlap weighting technique.Results: Contrary to bivariate analyses, in propensity score-controlled regression models, maternal smoking throughout pregnancy was no longer significantly associated with offspring emotional or behavioural difficulties. Maternal heavy smoking (≥10cigarettes/day) remained significantly associated with intermediate levels of conduct problems (RR 1.25 95%CI 1.19-1.31)Conclusion: The association between maternal smoking in pregnancy and offspring emotional and behavioural difficulties appears to be largely explained by women’s other characteristics. However, maternal heavy smoking appears to be related to offspring behavioural difficulties beyond the role of confounding characteristics. |
| Document Type: |
article in journal/newspaper |
| Language: |
English |
| DOI: |
10.1093/ntr/ntad023 |
| Availability: |
https://hal.science/hal-04026996; https://hal.science/hal-04026996v2/document; https://hal.science/hal-04026996v2/file/NTR%2002.2023.pdf; https://doi.org/10.1093/ntr/ntad023 |
| Rights: |
https://about.hal.science/hal-authorisation-v1/ ; info:eu-repo/semantics/OpenAccess |
| Accession Number: |
edsbas.DCF0F3AD |
| Database: |
BASE |