| Title: |
Short- and long-term sex-dependent effects of a nutritional supplement after hatching on growth, metabolism and gut microbiota in broiler chickens |
| Authors: |
Leterrier, Christine; Collin, Anne; Kempf, Florent; Zemb, Olivier; Cauquil, Laurent; Cailleau-Audouin, E.; Chartrin, Pascal; Parias, C.; Delaveau, J.; Rat, C.; Germain, K.; Guilloteau, Laurence, A. |
| Contributors: |
Physiologie de la reproduction et des comportements Nouzilly (PRC); Université de Tours (UT)-Centre National de la Recherche Scientifique (CNRS)-Institut National de Recherche pour l’Agriculture, l’Alimentation et l’Environnement (INRAE); Biologie des Oiseaux et Aviculture (BOA - UMR 0083); Université de Tours (UT)-Institut National de Recherche pour l’Agriculture, l’Alimentation et l’Environnement (INRAE); Infectiologie et Santé Publique (ISP); Génétique Physiologie et Systèmes d'Elevage (GenPhySE); École nationale vétérinaire de Toulouse (ENVT); Institut National Polytechnique (Toulouse) (Toulouse INP); Communauté d'universités et établissements de Toulouse (Comue de Toulouse)-Communauté d'universités et établissements de Toulouse (Comue de Toulouse)-Institut National Polytechnique (Toulouse) (Toulouse INP); Communauté d'universités et établissements de Toulouse (Comue de Toulouse)-Communauté d'universités et établissements de Toulouse (Comue de Toulouse)-École nationale supérieure agronomique de Toulouse (ENSAT, INP-ENSAT, AgroToulouse, INP-AgroToulouse); Communauté d'universités et établissements de Toulouse (Comue de Toulouse)-Communauté d'universités et établissements de Toulouse (Comue de Toulouse)-Institut National de Recherche pour l’Agriculture, l’Alimentation et l’Environnement (INRAE)-Ecole d'Ingénieurs de Purpan (EI Purpan); Communauté d'universités et établissements de Toulouse (Comue de Toulouse); Unité Expérimentale Avicole de Tours (UE PEAT); Institut National de Recherche pour l’Agriculture, l’Alimentation et l’Environnement (INRAE); Systèmes d'Elevage Avicoles Alternatifs (UE EASM); This research was supported by a grant from the Integrated Management of Animal Health Metaprogram of INRAE for the GISA-WHELP project (www.gisa.inra.fr/en). Integrated Management of Animal Health Metaprogram of INRAE for the GISA-WHELP project (www.gisa.inra.fr/en). |
| Source: |
ISSN: 0007-1668. |
| Publisher Information: |
CCSD; Taylor & Francis |
| Publication Year: |
2025 |
| Collection: |
Université François-Rabelais de Tours: HAL |
| Subject Terms: |
physiology; hatching; gut microbiota; metabolism; stress; growth; nutrition; gut; oxidative stress; metabolites; [SDV]Life Sciences [q-bio]; [SDV.BA.MVSA]Life Sciences [q-bio]/Animal biology/Veterinary medicine and animal Health |
| Description: |
International audience ; 1. In chicken production, a delay occurs between hatching and placement in the rearing building. This work analysed the effects of this experience on growth, metabolism, and caecal microbiota and tested whether a nutritional supplement (SUP) could mitigate these effects. 2. Chicks were placed directly in a rearing room (Control: C) or were exposed to a 24 h period without feed and water before being placed (Delayed: D). During the 24 h period, half of each group was provided with a SUP. 3. The D effect reduced body weight until d 27 in females (p = 0.017) and d 34 in males (p = 0.015). On d 1, the D group had reduced plasma triglycerides (TG) and increased uric acid (UA), total antioxidant status (TAS) and liver thiobarbituric acid reactive species in both sexes (p < 0.050). On d 34, the D group had increased UA and TAS only in females. It increased the alpha-diversity of microbiota in males (d 12 p = 0.036; d 34 p = 0.038) and the alpha-diversity in females on d 34 (p = 0.008). Changes in microbiota composition in both males and females were observed until d 34 at the genus level. 4. On d 1, the SUP increased glucose concentration in D and C group males (p = 0.001) and females (p = 0.002). The decrease in TG and increase in UA concentrations and TAS in chicks from the D group were mitigated by the SUP in females. On d 34, SUP reduced the haptoglobin-like activity in D and C group males (p = 0.041) and increased the TG concentration in C group males (p = 0.016). The SUP had little effect on the caecal microbiota. 5. Delayed placement induced long-lasting effects on growth, metabolism, and caecal microbiota composition. The effects of a nutritional supplement were variable and sex-dependent. |
| Document Type: |
article in journal/newspaper |
| Language: |
English |
| Relation: |
info:eu-repo/semantics/altIdentifier/pmid/40052800; PUBMED: 40052800; WOS: 001439632600001 |
| DOI: |
10.1080/00071668.2025.2465350 |
| Availability: |
https://hal.inrae.fr/hal-04998526; https://hal.inrae.fr/hal-04998526v1/document; https://hal.inrae.fr/hal-04998526v1/file/Delay-Supply-manuscript-Leterrier-2025.pdf; https://doi.org/10.1080/00071668.2025.2465350 |
| Rights: |
https://creativecommons.org/licenses/by/4.0/ ; info:eu-repo/semantics/OpenAccess |
| Accession Number: |
edsbas.DD15CC38 |
| Database: |
BASE |