| Title: |
Stroke- on- Awakening: Safety of CT-CTA Based Selection for Reperfusion Therapy |
| Authors: |
Simerpreet Bal; Rohit Bhatia; Nandavar Shobha; Bijoy K. Menon; Sung Il Sohn; Mayank Goyal; Andrew M. Demchuk; Michael D. Hill; the Calgary CTA group |
| Contributors: |
손성일; Sohn, Sung Il; Dept. of Neurology (신경과학) |
| Publisher Information: |
School of Medicine |
| Publication Year: |
2014 |
| Collection: |
Keimyung University Medical Library: KUMeL Repository |
| Description: |
Background: We studied the safety of use of acute reperfusion therapies in patients with stroke- on- awakening using a computed tomographic angiography (Cta) based large vessel occlusion-good scan paradigm in clinical routine. Methods: the Cta database of the Calgary stroke program was reviewed for the period January 2003-March 2010. patients with stroke-on-awakening with large artery occlusions on Cta, who received conservative, iV thrombolytic and/or endovascular treatment at discretion of the attending stroke neurologist were analyzed. time of onset was defined by the time last seen or known to be normal. Baseline non-contrast Ct scan (nCCt) alberta Stroke program early Ct Score (aSpeCtS) > 7 was considered a good scan. hemorrhage was defined on follow-up brain imaging using eCaSS 3 criteria. independence (mrS≤2) at three months was considered a good clinical outcome. Standard descriptive statistics and multivariable analysis were done. Results: among 532 patients with large artery occlusions, 70 patients with stroke-on-awakening (13.1%) were identified. the median age was 69.5 (iQr 24) and 41 (58.6%) were female; 41 (58.6%) received anti-platelets only and 29 (41.4%) received thrombolytic treatment [iV-12 (17.1%), iV/ia-12 (17.1%) and ia-5(7.1%)]. unadjusted analysis showed that baseline nCCt aSpeCtS ≤ 7 (p=0.002) and higher nihSS scores (p=0.018) were associated with worse outcomes. there were no ph2 hemorrhages in the iV thrombolytic or endovascular treated group. functional outcome was not different by treatment. Conclusion: When carefully selected using Ct –Cta, by a good scan (aSpeCtS > 7) occlusion paradigm, acute reperfusion therapies in patients with stroke-on-awakening can be performed safely in clinical routine. ; restriction |
| Document Type: |
article in journal/newspaper |
| Language: |
unknown |
| ISSN: |
0317-1671 |
| Relation: |
Canadian Journal of Neurological Sciences, Vol.41(2) : 182-186, 2014; oak-aaa-4459; http://kumel.medlib.dsmc.or.kr/handle/2015.oak/34472 |
| DOI: |
10.1017/S0317167100016553 |
| Availability: |
http://kumel.medlib.dsmc.or.kr/handle/2015.oak/34472; https://doi.org/10.1017/S0317167100016553 |
| Rights: |
BY_NC_ND ; http://creativecommons.org/licenses/by-nc-nd/2.0/kr |
| Accession Number: |
edsbas.DD8D28DB |
| Database: |
BASE |