| Title: |
A multi-valent polymyxin-based fluorescent probe for the detection of Gram-negative infections† |
| Authors: |
Sharma, Richa; Rodriguez Rios, Maria; Crossland, James; Septiyana, Maulida; Megia-Fernandez, Alicia; Klausen, Maxime; Bradley, Mark |
| Publisher Information: |
Royal Society of Chemistry |
| Publication Year: |
2024 |
| Collection: |
DIGIBUG: Repositorio Institucional de la Universidad de Granada |
| Description: |
Amulti-branched fluorogenic probe for the rapid and specific detection of Gram-negative bacteria is reported. ThreeGram-negative-targeting azidomodified polymyxins were clicked onto a trivalent scaffold functionalised with the environmental green-emitting fluorophore 7-nitrobenz-2-oxa- 1,3-diazole. The probe allowedwash-free detection of target bacteriawith increased sensitivity and lower limits of detection compared to monovalent probes. |
| Document Type: |
article in journal/newspaper |
| Language: |
English |
| Relation: |
Sharma, R. et. al. J. Mater. Chem. B, 2025. [https://doi.org/10.1039/d4tb01786b]; https://hdl.handle.net/10481/98502 |
| DOI: |
10.1039/d4tb01786b |
| Availability: |
https://hdl.handle.net/10481/98502; https://doi.org/10.1039/d4tb01786b |
| Rights: |
Atribución 4.0 Internacional ; http://creativecommons.org/licenses/by/4.0/ ; open access |
| Accession Number: |
edsbas.DDA22E7D |
| Database: |
BASE |