| Title: |
Predictive power of Oxygen Desaturation Index (ODI) and Apnea-Hypopnea Index (AHI) in detecting long-term neurocognitive and psychosocial outcomes of sleep-disordered breathing in children: a questionnaire-based study |
| Authors: |
Zaffanello M.; Ferrante G.; Zoccante L.; Ciceri M. L.; Nosetti L.; Tenero L.; Piazza M.; Piacentini G. |
| Contributors: |
Zaffanello, M.; Ferrante, G.; Zoccante, L.; Ciceri, M. L.; Nosetti, L.; Tenero, L.; Piazza, M.; Piacentini, G. |
| Publication Year: |
2023 |
| Collection: |
IRInSubria - Institutional Repository Insubria (Università degli Studi dell’Insubria) |
| Subject Terms: |
children; home respiratory polygraphy; obstructive apnea–hypopnea index; oxygen desaturation index; quality of life; questionnaire; sleep disordered breathing |
| Description: |
Pediatric obstructive sleep apnea can negatively affect children's neurocognitive function and development, hindering academic and adaptive goals. Questionnaires are suitable for assessing neuropsychological symptoms in children with sleep-disordered breathing. The study aimed to evaluate the effectiveness of using the Oxygen Desaturation Index compared to the Obstructive Apnea-Hypopnea Index in predicting long-term consequences of sleep-disordered breathing in children. We conducted a retrospective analysis of respiratory polysomnography recordings from preschool and school-age children (mean age: 5.8 ± 2.8 years) and followed them up after an average of 3.1 ± 0.8 years from the home-based polysomnography. We administered three validated questionnaires to the parents/caregivers of the children by phone. Our results showed that children with an Oxygen Desaturation Index (ODI) greater than one event per hour exhibited symptoms in four domains (physical, school-related, Quality of Life [QoL], and attention deficit hyperactivity disorder [ADHD]) at follow-up, compared to only two symptoms (physical and school-related) found in children with an Obstructive Apnea-Hypopnea Index greater than one event per hour at the time of diagnosis. Our study also found a significant correlation between the minimum SpO2 (%) recorded at diagnosis and several outcomes, including Pediatric Sleep Questionnaire (PSQ) scores, physical, social, and school-related outcomes, and ADHD index at follow-up. These results suggest that the Oxygen Desaturation Index could serve as a valuable predictor of long-term symptoms in children with sleep-disordered breathing, which could inform treatment decisions. Additionally, measuring minimum SpO2 levels may help assess the risk of developing long-term symptoms and monitor treatment outcomes. |
| Document Type: |
article in journal/newspaper |
| File Description: |
ELETTRONICO |
| Language: |
English |
| Relation: |
info:eu-repo/semantics/altIdentifier/pmid/37176501; info:eu-repo/semantics/altIdentifier/wos/WOS:000987289800001; volume:12; issue:9; numberofpages:13; journal:JOURNAL OF CLINICAL MEDICINE; https://hdl.handle.net/11383/2168083 |
| DOI: |
10.3390/jcm12093060 |
| Availability: |
https://hdl.handle.net/11383/2168083; https://doi.org/10.3390/jcm12093060 |
| Rights: |
info:eu-repo/semantics/openAccess |
| Accession Number: |
edsbas.DDD35390 |
| Database: |
BASE |