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Observed impact of skin substitutes in lower extremity diabetic ulcers: lessons from the Medicare Database (2015–2018)

Title: Observed impact of skin substitutes in lower extremity diabetic ulcers: lessons from the Medicare Database (2015–2018)
Authors: Armstrong, David G; Tettelbach, William H; Chang, Thomas J; De Jong, Julie L; Glat, Paul M; Hsu, Jeffrey H; Kelso, Martha R; Niezgoda, Jeffrey A; Tucker, Travis L; Labovitz, Jonathan M
Source: Journal of Wound Care ; volume 30, issue Sup7, page S5-S16 ; ISSN 0969-0700 2052-2916
Publisher Information: Mark Allen Group
Publication Year: 2021
Description: Objective: To evaluate large propensity-matched cohorts to assess outcomes in patients receiving advanced treatment (AT) with skin substitutes for lower extremity diabetic ulcers (LEDUs) versus no AT (NAT) for the management of LEDUs. Method: The Medicare Limited Dataset (1 October 2015 through 2 October 2018) were used to retrospectively analyse people receiving care for a LEDU treated with AT or NAT (propensity-matched Group 1). Analysis included major and minor amputations, emergency department (ED) visits and hospital readmissions. In addition, AT following parameters for use (FPFU) was compared with AT not FPFU (propensity-matched Group 2). A paired t-test was used for comparisons of the two groups. For comparisons of three groups, the Kruskal–Wallis test was used. A Bonferroni correction was performed when multiple comparisons were calculated. Results: There were 9,738,760 patients with a diagnosis of diabetes, of whom 909,813 had a LEDU. In propensity-matched Group 1 (12,676 episodes per cohort), AT patients had statistically fewer minor amputations (p=0.0367), major amputations (p
Document Type: article in journal/newspaper
Language: English
DOI: 10.12968/jowc.2021.30.sup7.s5
DOI: 10.12968/jowc.2021.30.Sup7.S5
Availability: https://doi.org/10.12968/jowc.2021.30.sup7.s5; http://www.magonlinelibrary.com/doi/pdf/10.12968/jowc.2021.30.Sup7.S5
Accession Number: edsbas.DDE3A2A3
Database: BASE