| Title: |
Barriers and Facilitators to Delivering Multifactorial Risk Assessment and Communication for Personalized Breast Cancer Screening: A Qualitative Study Exploring Implementation in Canada. |
| Authors: |
Walker, Meghan J; Neely, Anna; Antoniou, Antonis C; Broeders, Mireille JM; Brooks, Jennifer D; Carver, Tim; Chiquette, Jocelyne; Easton, Douglas F; Eisen, Andrea; Eloy, Laurence; Evans, D Gareth R; Fienberg, Samantha; Joly, Yann; Kim, Raymond H; Knoppers, Bartha M; Lofters, Aisha K; Nabi, Hermann; Pashayan, Nora; Stockley, Tracy L; Dorval, Michel; Simard, Jacques; Chiarelli, Anna M |
| Publisher Information: |
MDPI AG; //doi.org/10.3390/curroncol32030155 |
| Publication Year: |
2025 |
| Collection: |
Apollo - University of Cambridge Repository |
| Subject Terms: |
barriers; breast cancer screening; implementation; personalized screening; qualitative research; risk-stratification; Humans; Breast Neoplasms; Female; Risk Assessment; Early Detection of Cancer; Canada; Communication; Prospective Studies; Middle Aged; Adult |
| Description: |
Many jurisdictions are considering a shift to risk-stratified breast cancer screening; however, evidence on the feasibility of implementing it on a population scale is needed. We conducted a prospective cohort study in the PERSPECTIVE I&I project to produce evidence on risk-stratified breast screening and recruited 3753 participants to undergo multifactorial risk assessment from 2019-2021. This qualitative study explored the perspectives of study personnel on barriers and facilitators to delivering multifactorial risk assessment and risk communication. One focus group and three one-on-one interviews were conducted and a thematic analysis conducted which identified five themes: (1) barriers and facilitators to recruitment for multifactorial risk assessment, (2) barriers and facilitators to completion of the risk factor questionnaire, (3) additional resources required to implement multifactorial risk assessment, (4) the need for a person-centered approach, and (5) and risk literacy. While risk assessment and communication processes were successful overall, key barriers were identified including challenges with collecting comprehensive breast cancer risk factor information and limited resources to execute data collection and risk communication activities on a large scale. Risk assessment and communication processes will need to be optimized for large-scale implementation to ensure they are efficient but robust and person-centered. ; Genome Canada (#13529), the Canadian Institutes for Health Research (#155865), the Québec Ministry of Economy, Science and Innovation through Génome Québec, the Québec Breast Cancer Foundation, the CHU de Québec Foundation, the CHU de Québec–Université Laval Research Center and the Ontario Research Fund. A.C.A and T.C. are supported by Cancer Research UK grant: PPRPGM-Nov20\100002. |
| Document Type: |
article in journal/newspaper |
| File Description: |
application/pdf |
| Language: |
English |
| Relation: |
https://www.repository.cam.ac.uk/handle/1810/380896; https://doi.org/10.17863/CAM.116331 |
| DOI: |
10.17863/CAM.116331 |
| Availability: |
https://www.repository.cam.ac.uk/handle/1810/380896; https://doi.org/10.17863/CAM.116331 |
| Rights: |
Attribution 4.0 International ; https://creativecommons.org/licenses/by/4.0/ |
| Accession Number: |
edsbas.DDFBBD6C |
| Database: |
BASE |