| Title: |
When should clinicians suspect group Astreptococcusempyema in children? A multicentre case–control study in French tertiary care centres |
| Authors: |
Bellulo, Sophia; Sommet, Julie; Lévy, Corinne; Gillet, Yves; Hees, Laure; Lorrot, Mathie; Gras-Le-Guen, Christèle; Craiu, Irina; Dubos, François; Minodier, Philippe; Biscardi, Sandra; Dommergues, Marie-Aliette; Béchet, Stéphane; Bidet, Philippe; Alberti, Corinne; Cohen, Robert; Faye, Albert |
| Source: |
Archives of Disease in Childhood ; volume 101, issue 8, page 731-735 ; ISSN 0003-9888 1468-2044 |
| Publisher Information: |
BMJ |
| Publication Year: |
2016 |
| Description: |
Background The incidence of invasive group A streptococcus (GAS) infections is increasing worldwide, whereas there has been a dramatic decrease in pneumococcal invasive diseases. Few data describing GAS pleural empyema in children are available. Objective To describe the clinical and microbiological features, management and outcome of GAS pleural empyema in children and compare them with those of pneumococcal empyema. Design, setting and patients Fifty children admitted for GAS pleural empyema between January 2006 and May 2013 to 8 hospitals participating in a national pneumonia survey were included in a descriptive study and matched by age and centre with 50 children with pneumococcal empyema. Results The median age of the children with GAS pleural empyema was 2 (range 0.1–7.6) years. Eighteen children (36%) had at least one risk factor for invasive GAS infection (corticosteroid use and/or current varicella). On admission, 37 patients (74%) had signs of circulatory failure, and 31 (62%) had a rash. GAS was isolated from 49/50 pleural fluid samples and from one blood culture. The commonest GAS genotype was emm1 (n=17/22). Two children died (4%). Children with GAS empyema presented more frequently with a rash (p |
| Document Type: |
article in journal/newspaper |
| Language: |
English |
| DOI: |
10.1136/archdischild-2015-309831 |
| Availability: |
https://doi.org/10.1136/archdischild-2015-309831; https://syndication.highwire.org/content/doi/10.1136/archdischild-2015-309831 |
| Accession Number: |
edsbas.DEFEC642 |
| Database: |
BASE |