| Title: |
Canadian Women's Attitudes Toward Receiving Personalized Breast Cancer Risk Information: Insights From the PERSPECTIVE I&I Project. |
| Authors: |
Brooks, Jennifer D; Blackmore, Kristina M; Ngo, Nguyet NM; Walker, Meghan J; Chang, Amy; Lambert-Côté, Laurence; Turgeon, Annie; Lofters, Aisha K; Nabi, Hermann; Antoniou, Antonis C; Bell, Kathleen A; Broeders, Mireille JM; Carver, Tim; Chiquette, Jocelyne; Després, Philippe; Easton, Douglas F; Eisen, Andrea; Eloy, Laurence; Evans, D Gareth; Fienberg, Samantha; Joly, Yann; Kim, Raymond H; Kim, Shana J; Knoppers, Bartha M; Paquette, Jean-Sebastien; Pashayan, Nora; Sheppard, Amanda J; Stockley, Tracy L; Dorval, Michel; Simard, Jacques; Chiarelli, Anna M |
| Publisher Information: |
Elsevier; Department of Public Health and Primary Care, Cancer Genetic Epidemiology; //doi.org/10.1016/j.clbc.2025.12.009 |
| Publication Year: |
2026 |
| Collection: |
Apollo - University of Cambridge Repository |
| Subject Terms: |
Breast cancer risk-stratified screening; Breast screening; Perceived risk; Personalized risk communication; Risk prediction; Humans; Female; Breast Neoplasms; Middle Aged; Adult; Aged; Early Detection of Cancer; Risk Assessment; Health Knowledge; Attitudes; Practice; Ontario; Surveys and Questionnaires; Quebec; Canada |
| Description: |
BACKGROUND: Risk-stratified breast cancer screening has been proposed as an alternative to the age-based approach currently used by most screening programs. This study, part of the Canadian PERSPECTIVE I&I project, examined perceived advantages and disadvantages of learning your breast cancer risk category and associated screening plans. METHOD: Women aged 40 to 69 from Ontario and Quebec (N = 3319) had multifactorial risk assessments using the CanRisk tool. Risk categories (average [78.9%], higher than average [16.4%], high [4.6%]) were communicated along with screening plans. Participants completed questionnaires on attitudes toward learning their risk before, at the time of, and 1 year later risk communication. Participant characteristics associated with these attitudes were assessed using multinomial logistic regression. RESULTS: At the time of risk communication, most participants (72.9%) perceived ``Easing worry'' as an advantage of learning their risk. However, participants at higher risk were more likely to report that it did not ease their worry. Visible minority participants (OR = 1.86, 95% CI, 1.16, 2.98) and those with lower education attainment were more likely to view "complicated information" as a disadvantage (College/Apprenticeship/Trades: OR = 1.54, 95% CI, 1.24, 1.92; High School or below: OR = 1.77, 95% CI, 1.29, 2.42). Ontario participants were more likely to view risk communication as "information I do not want to know" (OR = 0.44, 95% CI, 0.32, 0.59) compared to Quebec participants. CONCLUSION: Most women responded positively to learning their breast cancer risk category and screening plan. Successful implementation of risk-stratified screening will require clear communication, healthcare provider support, and adaptation to regional resources. |
| Document Type: |
article in journal/newspaper |
| File Description: |
Print-Electronic; application/pdf |
| Language: |
English |
| Relation: |
https://www.repository.cam.ac.uk/handle/1810/399201; https://doi.org/10.17863/CAM.127826 |
| DOI: |
10.17863/CAM.127826 |
| Availability: |
https://www.repository.cam.ac.uk/handle/1810/399201; https://doi.org/10.17863/CAM.127826 |
| Rights: |
Attribution 4.0 International ; https://creativecommons.org/licenses/by/4.0/ |
| Accession Number: |
edsbas.DFA2706A |
| Database: |
BASE |