| Title: |
Treated incidence of psychotic disorders in the multinational EU-GEI study |
| Authors: |
Jongsma Hannah E; Gayer-Anderson Charlotte; Lasalvia Antonio; Quattrone Diego; Mulè Alice; Szöke Andrei; Selten Jean-Paul; Turner Caitlin; Arango Celso; Tarricone Ilaria; Berardi Domenico; Tortelli Andrea; Llorca Pierre-Michel; de Haan Lieuwe; Bobes Julio; Bernardo Miguel; Sanjuán Julio; Santos José Luis; Arrojo Manuel; Del-Ben Cristina Marta; Menezes Paulo Rossi; Murray Robin M; Rutten Bart P; Jones Peter B; van Os Jim; Morgan Craig; Kirkbride James B; European Network of National Schizophrenia Networks Studying Gene-Environment Interactions Work Package 2 (EU-GEI WP2) Group; Ruggeri Mirella; Tosato Sarah; Bonetto Chiara; Cristofalo Doriana; as Study Group Members |
| Contributors: |
Jongsma Hannah, E; Gayer-Anderson, Charlotte; Lasalvia, Antonio; Quattrone, Diego; Mulè, Alice; Szöke, Andrei; Selten, Jean-Paul; Turner, Caitlin; Arango, Celso; Tarricone, Ilaria; Berardi, Domenico; Tortelli, Andrea; Llorca, Pierre-Michel; de Haan, Lieuwe; Bobes, Julio; Bernardo, Miguel; Sanjuán, Julio; Santos José, Lui; Arrojo, Manuel; Del-Ben Cristina, Marta; Menezes Paulo, Rossi; Murray Robin, M; Rutten Bart, P; Jones Peter, B; van Os, Jim; Morgan, Craig; Kirkbride James, B; European Network of National Schizophrenia Networks Studying Gene-Environment Interactions Work Package, 2 (EU-GEI WP2) Group; Ruggeri, Mirella; Tosato, Sarah; Bonetto, Chiara; Cristofalo, Doriana; as Study Group, Members |
| Publication Year: |
2018 |
| Collection: |
Università degli Studi di Verona: Catalogo dei Prodotti della Ricerca (IRIS) |
| Subject Terms: |
psychotic disorder; international multisite incidence study; EU-GEI Study; environmental risk factors |
| Description: |
Importance: Psychotic disorders contribute significantly to the global disease burden, yet the latest international incidence study of psychotic disorders was conducted in the 1980s. Objectives: To estimate the incidence of psychotic disorders using comparable methods across 17 catchment areas in 6 countries and to examine the variance between catchment areas by putative environmental risk factors. Design, Setting, and Participants: An international multisite incidence study (the European Network of National Schizophrenia Networks Studying Gene-Environment Interactions) was conducted from May 1, 2010, to April 1, 2015, among 2774 individuals from England (2 catchment areas), France (3 catchment areas), Italy (3 catchment areas), the Netherlands (2 catchment areas), Spain (6 catchment areas), and Brazil (1 catchment area) with a first episode of nonorganic psychotic disorders (International Statistical Classification of Diseases and Related Health Problems, Tenth Revision [ICD-10] codes F20-F33) confirmed by the Operational Criteria Checklist. Denominator populations were estimated using official national statistics. Exposures: Age, sex, and racial/ethnic minority status were treated as a priori confounders. Latitude, population density, percentage unemployment, owner-occupied housing, and single-person households were treated as catchment area-level exposures. Main Outcomes and Measures: Incidence of nonorganic psychotic disorders (ICD-10 codes F20-F33), nonaffective psychoses (ICD-10 codes F20-F29), and affective psychoses (ICD-10 codes F30-F33) confirmed by the Operational Criteria Checklist. Results: A total of 2774 patients (1196 women and 1578 men; median age, 30.5 years [interquartile range, 23.0-41.0 years]) with incident cases of psychotic disorders were identified during 12.9 million person-years at risk (crude incidence, 21.4 per 100 000 person-years; 95% CI, 19.4-23.4 per 100 000 person-years). A total of 2183 patients (78.7%) had nonaffective psychotic disorders. After direct standardization for age, ... |
| Document Type: |
article in journal/newspaper |
| File Description: |
STAMPA |
| Language: |
English |
| Relation: |
info:eu-repo/semantics/altIdentifier/pmid/29214289; info:eu-repo/semantics/altIdentifier/wos/WOS:000419177700009; volume:75; issue:1; firstpage:36; lastpage:46; numberofpages:11; journal:JAMA PSYCHIATRY; https://hdl.handle.net/11562/972050; https://doi.org/10.1001/jamapsychiatry.2017.3554 |
| DOI: |
10.1001/jamapsychiatry.2017.3554 |
| Availability: |
https://hdl.handle.net/11562/972050; https://doi.org/10.1001/jamapsychiatry.2017.3554 |
| Rights: |
info:eu-repo/semantics/openAccess ; license:Dominio pubblico ; license uri:http://creativecommons.org/publicdomain/zero/1.0/ |
| Accession Number: |
edsbas.DFEC6ECC |
| Database: |
BASE |