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Enantioseparation of planar chiral ferrocenes on cellulose-based chiral stationary phases: Benzoate versus carbamate pendant groups

Title: Enantioseparation of planar chiral ferrocenes on cellulose-based chiral stationary phases: Benzoate versus carbamate pendant groups
Authors: Dallocchio, Roberto; Dessì, Alessandro; Sechi, Barbara; Chankvetadze, Bezhan; Jibuti, Giorgi; Cossu, Sergio; Mamane, Victor; Peluso, Paola
Contributors: Dallocchio, Roberto; Dessì, Alessandro; Sechi, Barbara; Chankvetadze, Bezhan; Jibuti, Giorgi; Cossu, Sergio; Mamane, Victor; Peluso, Paola
Publication Year: 2023
Collection: Università Ca’ Foscari Venezia: ARCA (Archivio Istituzionale della Ricerca)
Subject Terms: cellulose-based chiral stationary phase; enantiomer elution order; enantioseparation; molecular dynamic; planar chiral ferrocenes; Settore CHIM/01 - Chimica Analitica; Settore CHEM-01/A - Chimica analitica
Description: In this study, the enantioseparation of 14 planar chiral ferrocenes containing halogen atoms, and methyl, iodoethynyl, phenyl, and 2-naphthyl groups, as substituents, was explored with a cellulose tris(4-methylbenzoate) (CMB)-based chiral column under multimodal elution conditions. n-Hexane/2-propanol (2-PrOH) 95:5 v/v, pure methanol (MeOH), and MeOH/water 90:10 v/v were used as mobile phases (MPs). With CMB, baseline enantioseparations were achieved for nine analytes with separation factors (alpha) ranging from 1.24 to 1.77, whereas only three analytes could be enantioseparated with 1.14
Document Type: article in journal/newspaper
File Description: STAMPA
Language: English
Relation: info:eu-repo/semantics/altIdentifier/pmid/36177685; info:eu-repo/semantics/altIdentifier/wos/WOS:000867315400001; volume:44; issue:1-2; firstpage:203; lastpage:216; numberofpages:14; journal:ELECTROPHORESIS; https://hdl.handle.net/10278/5082426; https://doi.org/10.1002/elps.202200205
DOI: 10.1002/elps.202200205
Availability: https://hdl.handle.net/10278/5082426; https://doi.org/10.1002/elps.202200205
Rights: info:eu-repo/semantics/openAccess
Accession Number: edsbas.E0763CEE
Database: BASE