| Title: |
Three-dimensional echocardiographic left atrial emptying fraction (3D LAEF) compared with traditional and novel diastolic dysfunction parameters in patients with chronic heart failure |
| Authors: |
Basile, P; Mazza, B; Carella, M C; Dicorato, M M; Falagario, A; Monitillo, F; Santoro, D; Dentamaro, I; Santobuono, V E; Forleo, C; Ciccone, M M; Guaricci, A I |
| Contributors: |
Basile, P; Mazza, B; Carella, M C; Dicorato, M M; Falagario, A; Monitillo, F; Santoro, D; Dentamaro, I; Santobuono, V E; Forleo, C; Ciccone, M M; Guaricci, A I |
| Publication Year: |
2025 |
| Collection: |
Università degli Studi di Bari Aldo Moro: CINECA IRIS |
| Subject Terms: |
Imaging; Echocardiography; 3D Echocardiography |
| Description: |
Background: Echocardiography represent an essential resource to assess left ventricular diastolic dysfunction (LVDD) in patients with Chronic Heart Failure (CHF). The diagnosis is multi-parametric by applying the criteria of 2016 ASE/EACVI guidelines. Alongside the traditional parameters adopted, new tools are emerging as valuable support in the diagnostic algorithm. Among these, the most remarkable are three-dimensional left atrial emptying fraction (3D LAEF) and PALS/PACS obtained with speckle-tracking (ST). However, their role in daily practice requires further investigations. Purpose: Our aim was to explore the role of 3D LAEF and its relationship with both traditional and novel parameters used for LVDD assessment in patients with CHF. Methods: An observational, cross-sectional, monocentric study was conducted enrolling 53 outpatient with CHF in a tertiary referral hospital from September 2024 to December 2024. Exclusion criteria were the presence of any of the following: atrial brillation or atrial arrhythmias during the examination, heart rate>100bpm, severe mitral regurgitation or moderate/severe mitral stenosis, mitral replacement with prosthetic valve, inadequate imaging quality. For each patient were collected clinical data and a transthoracic echocardiography with 2D, pulsed wave and tissue Doppler, 3D and ST evaluation were performed by two cardiologists with expertise in advanced echocardiography. Results: The mean age of the population was 66±11 years with a clear prevalence of male sex (83%). About one half of patients had a HFrEF (43%), 32% of cases had HFmrEF and the remaining HFpEF (25%). The median value of 3D Left Atrial Volume Index (LAVI) was 32 (IQR 12). According to the criteria ASE/EACVI, the majority of the population had a grade 1 LVDD (90%), while a grade 2 and 3 were found respectively in 6% and 4% of cases. Statistically signi cant correlations were found between 3DE LAEF and 3D LAVI (ρs = -0.47; p |
| Document Type: |
article in journal/newspaper |
| Language: |
English |
| Relation: |
info:eu-repo/semantics/altIdentifier/wos/WOS:001675510700001; volume:46; issue:Supplement_1; journal:EUROPEAN HEART JOURNAL; https://hdl.handle.net/11586/572461 |
| DOI: |
10.1093/eurheartj/ehaf784.128 |
| Availability: |
https://hdl.handle.net/11586/572461; https://doi.org/10.1093/eurheartj/ehaf784.128 |
| Accession Number: |
edsbas.E0922FA6 |
| Database: |
BASE |