| Title: |
Hormonal factors predictive of fertility in patients with breast cancer interrupting adjuvant endocrine therapy to attempt pregnancy in POSITIVE trial. |
| Authors: |
Demeestere, Isabelle; Niman, Samuel M; Partridge, Ann H; Diego, Daniela S; Kammler, Roswitha; Ruggeri, Monica; Colleoni, Marco Angelo; Shimizu, Chikako; Saura, Cristina; Gelmon, Karen A; Saetersdal, Anna B; Kroep, Judith R; Mailliez, Audrey; Amant, Frédéric; Ruız-Borrego, Manuel; Lee, Jeong Eon; Kataoka, Akemi; Walshe, Janice M; Takei, Junko; Borstnar, Simona; Borges, Virginia F; Saunders, Christobel; Susnjar, Snezana; Bjelic-Radisic, Vesna; Cardoso, Fatima; Meisel, Jane Lowe; Kawwass, Jennifer Fay; Spanic, Tanja; El-Abed, Sarra; Piccart-Gebhart, Martine; Korde, Larissa A; Goldhirsch, Aron; Gelber, Richard D; Pagani, Olivia; Azim, Hatem A; Peccatori, Fedro A; International Breast Cancer Study Group and the POSITIVE Trial Collaborators |
| Source: |
Breast, 83 |
| Publication Year: |
2025 |
| Collection: |
DI-fusion : dépôt institutionnel de l'Université libre de Bruxelles (ULB) |
| Subject Terms: |
Gynécologie; Cancérologie; Sciences biomédicales; Adult; Female; Humans; Pregnancy; Anti-Mullerian Hormone -- blood; Antineoplastic Agents; Hormonal; Breast Neoplasms -- drug therapy -- blood; Chemotherapy; Adjuvant; Fertility; Fertility Preservation -- methods; Follicle Stimulating Hormone -- blood; Ovarian Reserve -- physiology; Premenopause; Primary Ovarian Insufficiency -- blood; Progesterone -- blood; Prolactin -- blood; Thyrotropin -- blood; Assisted reproductive technology; Breast cancer; Ovarian reserve; Premature ovarian insufficiency |
| Description: |
The POSITIVE trial showed that premenopausal women with breast cancer (BC) can safely pause adjuvant endocrine treatment (ET) to attempt conception. 74 % of patients conceived spontaneously or through assisted reproductive technology (ART); Investigating hormonal factors that predict fertility was a key secondary endpoint. ; info:eu-repo/semantics/published |
| Document Type: |
article in journal/newspaper |
| File Description: |
2 full-text file(s): application/pdf | application/pdf |
| Language: |
English |
| Relation: |
uri/info:doi/10.1016/j.breast.2025.104547; uri/info:pmid/40743662; uri/info:pmcid/PMC12336806; https://dipot.ulb.ac.be/dspace/bitstream/2013/396394/5/DemeesterePOSITIVE2025.pdf; https://dipot.ulb.ac.be/dspace/bitstream/2013/396394/1/elsevier_380038.pdf |
| Availability: |
https://hdl.handle.net/2013/ULB-DIPOT:oai:dipot.ulb.ac.be:2013/396394; https://dipot.ulb.ac.be/dspace/bitstream/2013/396394/5/DemeesterePOSITIVE2025.pdf; https://dipot.ulb.ac.be/dspace/bitstream/2013/396394/1/elsevier_380038.pdf |
| Accession Number: |
edsbas.E1AF8430 |
| Database: |
BASE |