| Title: |
Feed supplementation with molybdenum complexes improves honey bee health |
| Authors: |
Fuior, Arcadie; Colin-Duchevet, Loïc; Cebotari, Valentina; Noël, Amélie; Ribaud, Isabelle; Gérard, Isabelle; Garbuz, Olga; Fregnaux, Mathieu; López, Xavier; Larcher, Virginie; Shestopalov, Michael; Solovieva, Anastasiya; Pozmogova, Tatiana; Gliga, Olesea; Railean, Nadejda; Cochard, Précillia; Poirot, Benjamin; Charistos, Leonidas; Hatjina, Fani; Somogyi, Andrea; Medjoubi, Kadda; Gaumer, Sébastien; Gulea, Aurelian; Toderas, Ion; Sandoz, Jean-Christophe; Floquet, Sébastien |
| Contributors: |
Institut Lavoisier de Versailles (ILV); Université de Versailles Saint-Quentin-en-Yvelines (UVSQ)-Institut de Chimie - CNRS Chimie (INC-CNRS)-Centre National de la Recherche Scientifique (CNRS); State University of Moldova; Evolution, génomes, comportement et écologie (EGCE); Institut de Recherche pour le Développement (IRD)-Université Paris-Saclay-Centre National de la Recherche Scientifique (CNRS); Institute of Zoology Chisinau; Academy of Sciences of Moldova (ASM); Laboratoire de Physique des 2 Infinis Irène Joliot-Curie (IJCLab); Institut National de Physique Nucléaire et de Physique des Particules du CNRS (IN2P3)-Université Paris-Saclay-Centre National de la Recherche Scientifique (CNRS); Université de Versailles Saint-Quentin-en-Yvelines (UVSQ); Etudes sur les sciences et les techniques (EST); Université Paris-Saclay; Department of Chemistry, Moldova State University; University Rovira i virgili = Universidad Rovira y Virgili = Universitat Rovira i Virgili (URV); Nikolaev Institute of Inorganic Chemistry Novosibirsk (NIC); Siberian Branch of the Russian Academy of Sciences (SB RAS); Apilab; Apinov (Apinov); Hellenic Agricultural Organization Demeter (HAO Demeter); Julius-Maximilians-Universität Würzburg = University of Würzburg Würsburg, Germany (JMU); Synchrotron SOLEIL (SSOLEIL); Centre National de la Recherche Scientifique (CNRS); Laboratoire de génétique et biologie cellulaire (LGBC) |
| Source: |
ISSN: 2052-1545. |
| Publisher Information: |
CCSD; Royal Society of Chemistry |
| Publication Year: |
2025 |
| Collection: |
Université de Versailles Saint-Quentin-en-Yvelines: HAL-UVSQ |
| Subject Terms: |
Bee health; dinuclear Molybdenum complexes; Dietary supplementation; Bee colony; Beehives; X-ray fluorescence XRF spectrometry; X-Ray photoelectron spectroscopy; [CHIM]Chemical Sciences; [SDV]Life Sciences [q-bio] |
| Description: |
International audience ; This study investigates the effects of dietary supplementation with molybdenum-based compounds on honey bee health. Among a series of dinuclear Mo(V) complexes, the most stable and non-toxic com- plexes were selected and tested over an extensive eight-year field campaign involving more than 700 beehives across diverse environmental conditions in Moldova, France, Greece and the United States. In a first part, we established that the administration of a few milligrams of the compounds Na-Mo2O4-EDTA or Li-Mo2O4-EDTA in spring or autumn enhanced colony performance: queen fecundity, hygienic behav- iour, and honey production increased, while Varroa destructor infestation rates and winter losses were substantially reduced. A second part of the work focused on understanding these effects in beehives. Hive monitoring showed that the Mo-containing syrup can be consumed over 1.5 months and is well assimilated by larvae and workers. In particular, Mo levels increased significantly in the head of the bees. X-ray fluorescence measurements demonstrated that Na-Mo2O4-EDTA increases Mo levels in the brain, neurolemma and hypopharyngeal glands, which play a crucial role in honey bee health. The metabolism of Mo complexes was addressed using X-ray photoelectron spectroscopy (XPS) on bee fæces, which revealed that the complexes are oxidized into Mo(VI), suggesting that Mo complexes may function as anti- oxidant agents in bees. These findings offer promising solutions for the beekeeping industry, struggling with weakening honey bee colonies. |
| Document Type: |
article in journal/newspaper |
| Language: |
English |
| DOI: |
10.1039/d5qi00878f |
| Availability: |
https://hal.science/hal-05156949; https://hal.science/hal-05156949v1/document; https://hal.science/hal-05156949v1/file/d5qi00878f.pdf; https://doi.org/10.1039/d5qi00878f |
| Rights: |
https://creativecommons.org/licenses/by/4.0/ ; info:eu-repo/semantics/OpenAccess |
| Accession Number: |
edsbas.E1CB7666 |
| Database: |
BASE |