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GEOGRAPHIC ACCESS DISPARITIES TO CLINICAL TRIALS IN RETINOPATHY OF PREMATURITY IN THE UNITED STATES

Title: GEOGRAPHIC ACCESS DISPARITIES TO CLINICAL TRIALS IN RETINOPATHY OF PREMATURITY IN THE UNITED STATES
Authors: Soares, Rebecca R.; Cai, Louis Z.; Bowe, Theodore; Samuelson, Annika G.; Liu, Catherine K.; Parikh, Devayu; Patel, Samir N.; Hinkle, John W.; Yonekawa, Yoshihiro
Source: Retina ; volume 41, issue 11, page 2253-2260 ; ISSN 0275-004X
Publisher Information: Ovid Technologies (Wolters Kluwer Health)
Publication Year: 2021
Description: Background/Purpose: To identify geographic and socioeconomic variables predictive of residential proximity to retinopathy of prematurity (ROP) clinical trial locations. Methods: This cross-sectional epidemiological study used census tract–level data from three national public data sets and trial-level data from ClinicalTrials.gov. Socioeconomic predictors of driving distance and time to the nearest ROP clinical trial location were identified. Primary outcomes were time >60 minutes and distance >60 miles traveled to the nearest ROP clinical trial site. Results: Multivariate analysis showed that residents were more likely to travel >60 minutes to the nearest ROP clinical trial site if they lived in census tracts that were rural (adjusted odds ratio 1.20, P = 0.0002), had higher percentages of the population living ≤ federal poverty level (fourth quartile vs. first quartile, adjusted odds ratio 1.19, P < 0.0001), or had less education (associate vs. bachelor's degree, adjusted odds ratio 1.01, P
Document Type: article in journal/newspaper
Language: English
DOI: 10.1097/iae.0000000000003218
DOI: 10.1097/IAE.0000000000003218
Availability: https://doi.org/10.1097/iae.0000000000003218; https://journals.lww.com/10.1097/IAE.0000000000003218
Accession Number: edsbas.E20CBC0E
Database: BASE