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Influence of immunosuppression on seroconversion against SARS‐CoV‐2 in two kidney transplant recipients

Title: Influence of immunosuppression on seroconversion against SARS‐CoV‐2 in two kidney transplant recipients
Authors: Wang, Aileen X; Cardona, Orlando Quintero; Ho, Dora Y; Busque, Stephan; Lenihan, Colin R
Source: Transplant Infectious Disease, vol 23, iss 1
Publisher Information: eScholarship, University of California
Publication Year: 2021
Collection: University of California: eScholarship
Subject Terms: 32 Biomedical and Clinical Sciences (for-2020); 3202 Clinical Sciences (for-2020); Coronaviruses (rcdc); Kidney Disease (rcdc); Emerging Infectious Diseases (rcdc); Transplantation (rcdc); Infectious Diseases (rcdc); Organ Transplantation (rcdc); Clinical Research (rcdc); Infection (hrcs-hc); Renal and urogenital (hrcs-hc); 3 Good Health and Well Being (sdg); Aged (mesh); Female (mesh); Humans (mesh); Immunocompromised Host (mesh); Immunosuppressive Agents (mesh); Kidney Transplantation (mesh); Middle Aged (mesh); SARS-CoV-2 (mesh); Seroconversion (mesh); Transplant Recipients (mesh); antibodies; COVID-19; immunosuppression; RT-PCR; SARS-CoV-2; seroconversion
Description: Solid organ transplant recipients are at risk for infectious complications due to chronic immunosuppression. The outbreak of coronavirus disease 2019 (COVID-19) in the United States has raised growing concerns for the transplant patient population. We seek to add to the current limited literature on COVID-19 in transplant recipients by describing the clinical course of two kidney transplant recipients with SARS-CoV-2 infection monitored by both RT-PCR and serology. Through careful adjustment of their immunosuppression regimen, both patients had excellent recovery with intact graft function and development of anti-SARS-CoV-2 antibodies.
Document Type: article in journal/newspaper
File Description: application/pdf
Language: unknown
Relation: qt2rc1d8cr; https://escholarship.org/uc/item/2rc1d8cr; https://escholarship.org/content/qt2rc1d8cr/qt2rc1d8cr.pdf
DOI: 10.1111/tid.13423
Availability: https://escholarship.org/uc/item/2rc1d8cr; https://escholarship.org/content/qt2rc1d8cr/qt2rc1d8cr.pdf; https://doi.org/10.1111/tid.13423
Rights: public
Accession Number: edsbas.E22FE32B
Database: BASE