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Prenatal Prediction of Outcome by Fetal Gastroschisis in a Tertiary Referral Center

Title: Prenatal Prediction of Outcome by Fetal Gastroschisis in a Tertiary Referral Center
Authors: Katharina Nitzsche; Guido Fitze; Mario Rüdiger; Cahit Birdir
Source: Diagnostics, Vol 10, Iss 540, p 540 (2020)
Publisher Information: MDPI AG
Publication Year: 2020
Collection: Directory of Open Access Journals: DOAJ Articles
Subject Terms: gastroschisis; exomphalos; omphalocele; prenatal diagnosis; surgery; Medicine (General); R5-920
Description: The aim of this study was to find a prenatal parameter to be able to predict possible prenatal complications or postnatal surgical options, thus allowing the fetal medicine specialist, together with pediatric surgeons and neonatologists, to improve the counseling of the parents and to determine the timing of delivery and therapy. This was a retrospective analysis of prenatal diagnosis and outcome of fetuses with 34 cases of gastroschisis between the years 2007 and 2017. A total of 34 fetuses with gastroschisis were examined and 33 outcomes registered: 22 cases of simple gastroschisis (66.7%) and 11 cases of complex gastroschisis (33.3%). A cut-off value of 18 mm for intraabdominal bowel dilatation (IABD) showed a positive predictive value (PPV) of 100% for predicting simple gastroschisis. IABD gives the best prediction for simple versus complex gastroschisis (cut-off of 18 mm). Extra-abdominal bowel dilatation (EABD) cut-off values of 10 mm and 18 mm showed low sensitivity and specificity to predict complex gastroschisis.
Document Type: article in journal/newspaper
Language: English
Relation: https://www.mdpi.com/2075-4418/10/8/540; https://doaj.org/toc/2075-4418; https://doaj.org/article/9fe0983aa0fb41c7b13599be8dcf5119
DOI: 10.3390/diagnostics10080540
Availability: https://doi.org/10.3390/diagnostics10080540; https://doaj.org/article/9fe0983aa0fb41c7b13599be8dcf5119
Accession Number: edsbas.E236FBEC
Database: BASE