Towards a new Value-based scenario for the management of dementia in Italy: a SINdem delphi consensus study
| Title: | Towards a new Value-based scenario for the management of dementia in Italy: a SINdem delphi consensus study |
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| Authors: | Marra C.; Beccia F.; Caffarra P.; L'Abbate F.; Agosta F.; Benussi A.; Bonanni L.; Bruni A. C.; Bruno G.; Cappa S. F.; Cerami C.; Di Lorenzo F.; Ferrarese C.; Galimberti D.; Guarnieri B.; Mariani C.; Nacmias B.; Pantoni L.; Piccoli T.; Perani D.; Rainero I.; Tagliavini F.; Venneri A.; Boccia S.; Cagnin A.; Calabrò G. E.; Bozzali M.; Zuffi M.; Zanusso G.; Vista M.; Vacca A.; Tripi G.; Tognoni G.; Tiraboschi P.; Sucapane P.; Spallazzi M.; Sibilia G.; Sensi S.; Rubino E.; Rosso M.; Roncacci S.; Puccio G.; Plutino A.; Parnetti L.; Pardini M.; Parchi P.; Orsini A. V. M.; Musso A. M.; Mura G.; Monastero R.; Moda F.; Merlo P.; Mei D.; Mecocci P.; Giuseppina Mascia M.; Martorana A.; Marti A.; Marcon M.; Malagù S.; Luzzi S.; Luiselli D.; Luca A.; Isella V.; Imperiale D.; Iavarone A.; Guarino M.; Gragnaniello D.; Giubilei F.; Forloni G.; Floris G.; Fiori C.; Filippi M.; Farina E.; Fabi K.; Esposito S.; Di Giorgi L.; Della Rocca G.; De Togni L.; Colao R.; Ceci M.; Capellari S.; Canu E. D. G.; Bessi V.; Bellelli G.; Baschi R.; Babiloni C.; Bagnato S.; Arighi A.; Arabia G.; Angeloni R. |
| Contributors: | Marra, C; Beccia, F; Caffarra, P; L'Abbate, F; Agosta, F; Benussi, A; Bonanni, L; Bruni, A; Bruno, G; Cappa, S; Cerami, C; Di Lorenzo, F; Ferrarese, C; Galimberti, D; Guarnieri, B; Mariani, C; Nacmias, B; Pantoni, L; Piccoli, T; Perani, D; Rainero, I; Tagliavini, F; Venneri, A; Boccia, S; Cagnin, A; Calabrò, G; Bozzali, M; Zuffi, M; Zanusso, G; Vista, M; Vacca, A; Tripi, G; Tognoni, G; Tiraboschi, P; Sucapane, P; Spallazzi, M; Sibilia, G; Sensi, S; Rubino, E; Rosso, M; Roncacci, S; Puccio, G; Plutino, A; Parnetti, L; Pardini, M; Parchi, P; Orsini, A; Musso, A; Mura, G; Monastero, R; Moda, F; Merlo, P; Mei, D; Mecocci, P; Giuseppina Mascia, M; Martorana, A; Marti, A; Marcon, M; Malagù, S; Luzzi, S; Luiselli, D; Luca, A; Isella, V; Imperiale, D; Iavarone, A; Guarino, M; Gragnaniello, D; Giubilei, F; Forloni, G; Floris, G; Fiori, C; Filippi, M; Farina, E; Fabi, K; Esposito, S; Di Giorgi, L; Della Rocca, G; De Togni, L; Colao, R; Ceci, M; Capellari, S; Canu, E; Bessi, V; Bellelli, G; Baschi, R; Babiloni, C; Bagnato, S; Arighi, A; Arabia, G; Angeloni, R |
| Publisher Information: | Springer-Verlag Italia s.r.l.; IT |
| Publication Year: | 2025 |
| Collection: | Università degli Studi di Milano-Bicocca: BOA (Bicocca Open Archive) |
| Subject Terms: | Alzheimer care management; Biological diagnosi; Delphi consensu; Dementia; Disease modifying drug; Italy |
| Description: | This national expert-based Delphi-consensus aims at formulating recommendations on the management of dementia care in Italy. This effort seems important and timely given in light of a new scenario arising from a new biological definition of Alzheimer's disease (AD) and the availability of disease-modifying treatments (DMTs). Methods the Steering Committee of the Italian Neurological Society for dementia (SINdem) created appropriate statements. Invited SINdem experts were requested to vote on the statements according to a modified three-round Delphi method. Only those statements reaching Grade A (full agreement >= 75%) or B (overall agreement >= 80% and full disagreement < 5%) were included in the final document. Round answers' consistency was graded using the Cohen's k and within-class correlation coefficient. Results Forty-six experts voted on 20 statements, which focused on the following aspects: i) organization of care services from early diagnosis to the management of advanced clinical stages; ii) access to biomarkers for a biological diagnosis of AD; iii) requirements necessary for the administration of DMTs; iv) main actors and pathways for the management of patients suffering from cognitive disorders. At the end of the process, 4 statements (20%) received a Grade A consensus, while 16 (80%) reached a Grade B consensus. Although the responses reflect heterogeneity among Italian regions, there was a fair degree of consistency for all statements. Conclusion The high strength of this expert-based Delphi-consensus may offer guidance for improving the patient's journey of individuals with cognitive decline from a biological diagnosis to DMTs administration and may possibly offer hints to the Health Systems on dementia. |
| Document Type: | article in journal/newspaper |
| File Description: | STAMPA |
| Language: | English |
| Relation: | info:eu-repo/semantics/altIdentifier/pmid/40237973; info:eu-repo/semantics/altIdentifier/wos/WOS:001469527600001; volume:46; issue:7; firstpage:2913; lastpage:2923; numberofpages:11; journal:NEUROLOGICAL SCIENCES; https://hdl.handle.net/10281/554762 |
| DOI: | 10.1007/s10072-025-08143-5 |
| Availability: | https://hdl.handle.net/10281/554762; https://doi.org/10.1007/s10072-025-08143-5 |
| Rights: | info:eu-repo/semantics/openAccess ; license:Creative Commons ; license uri:http://creativecommons.org/licenses/by/4.0/ |
| Accession Number: | edsbas.E28ECB44 |
| Database: | BASE |