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Unattended versus Attended Blood Pressure Measurement: Relationship with Retinal Microcirculation

Title: Unattended versus Attended Blood Pressure Measurement: Relationship with Retinal Microcirculation
Authors: Paini, Anna; Agabiti Rosei, Claudia; De Ciuceis, Carolina; Aggiusti, Carlo; Bertacchini, Fabio; Cacciatore, Marco; Capellini, Sara; Gatta, Roberto; Malerba, Paolo; Stassaldi, Deborah; Rizzoni, Damiano; Salvetti, Massimo; Muiesan, Maria Lorenza
Contributors: Paini Anna; Agabiti Rosei Claudia; De Ciuceis Carolina; Aggiusti Carlo; Bertacchini Fabio; Cacciatore Marco; Capellini Sara; Gatta Roberto; Malerba Paolo; Stassaldi Deborah; Rizzoni Damiano; Salvetti Massimo; Muiesan Maria Lorenza
Publication Year: 2022
Collection: Università degli Studi di Brescia: OPENBS - Open Archive UniBS
Subject Terms: AOBP; adaptive optic; blood pressure measurement; media/lumen ratio; retinal arteriole; unattended blood pressure; wall-to-lumen ratio
Description: Though the relationship between both "attended" and "unattended" BP and several forms of target organ damage have been evaluated, data on retinal arteriolar alterations are lacking. The aim of our study was to evaluate the relationship between "attended" or "unattended" BP values and retinal arteriolar changes in consecutive individuals undergoing a clinical evaluation and assessment of retinal fundus at an ESH Excellence Centre. An oscillometric device programmed to perform 3 BP measurements, at 1 min intervals and after 5 min of rest was used on all individuals to measure BP with the patient alone in the room ("unattended") or in the presence of the physician ("attended") in the same day in a random order. The retinal arteriole's wall thickness (WT) was measured automatically by a localization algorithm as the difference between external (ED) and internal diameter (ID) by adaptive optics (RTX-1, Imagine Eyes, Orsay, Francia). Media-to-lumen ratio (WLR) of the retinal arterioles and cross-sectional area (WCSA) of the vascular wall were calculated. Results: One-hundred-forty-two patients were examined (mean age 57 +/- 12 yrs, 48% female, mean BMI 26 +/- 4). Among them, 60% had hypertension (84% treated) and 11% had type 2 diabetes mellitus. Unattended systolic BP (SBP) was lower as compared to attended SBP (129 +/- 14.8. vs. 122.1 +/- 13.6 mmHg, p < 0.0001). WLR was similarly correlated with unattended and attended SBP (r = 0.281, p < 0.0001 and r = 0.382, p < 0.0001) and with unattended and attended diastolic BP (r = 0.34, p < 0.001 and r = 0.29, p < 0.0001). The differences between correlations were not statistically significant (Steiger's Z test). Conclusion: The measurement of "unattended" or "attended" BP provides different values, and unattended BP is lower as compared to attended BP. In this study a similar correlation was observed between attended and unattended BP values and structural changes of retinal arterioles.
Document Type: article in journal/newspaper
Language: English
Relation: info:eu-repo/semantics/altIdentifier/pmid/36498540; info:eu-repo/semantics/altIdentifier/wos/WOS:000896194400001; volume:11; issue:23; journal:JOURNAL OF CLINICAL MEDICINE; https://hdl.handle.net/11379/603725
DOI: 10.3390/jcm11236966
Availability: https://hdl.handle.net/11379/603725; https://doi.org/10.3390/jcm11236966
Rights: info:eu-repo/semantics/openAccess
Accession Number: edsbas.E33FCC5A
Database: BASE