| Title: |
Ten-year follow-up after mitoxantrone induction for early highly active relapsing-remitting multiple sclerosis: An observational study of 100 consecutive patients |
| Authors: |
Lefort, Mathilde; Le Corre, G.; Le Page, E.; Rizzato, C.; Le Port, D.; Michel, L.; Kerbrat, A.; Leray, Emmanuelle; Edan, G. |
| Contributors: |
Arènes: politique, santé publique, environnement, médias (ARENES); Université de Rennes (UR)-Institut d'Études Politiques IEP - Rennes-École des Hautes Études en Santé Publique EHESP (EHESP)-Université de Rennes 2 (UR2)-Centre National de la Recherche Scientifique (CNRS); Centre d'Investigation Clinique Rennes (CIC); Université de Rennes (UR)-Centre Hospitalier Universitaire de Rennes CHU Rennes = Rennes University Hospital Pontchaillou -Institut National de la Santé et de la Recherche Médicale (INSERM); École des Hautes Études en Santé Publique EHESP (EHESP); Département Méthodes quantitatives en santé publique (METIS); Recherche sur les services et le management en santé (RSMS); Université de Rennes (UR)-École des Hautes Études en Santé Publique EHESP (EHESP)-Institut National de la Santé et de la Recherche Médicale (INSERM)-Centre National de la Recherche Scientifique (CNRS); Centre Hospitalier Universitaire de Rennes CHU Rennes = Rennes University Hospital Pontchaillou; Collectif de recherche handicap, autonomie et société inclusive (CoRHASI) |
| Source: |
ISSN: 0035-3787 ; Revue Neurologique ; https://ehesp.hal.science/hal-03588900 ; Revue Neurologique, 2022, 178 (6), pp.569-579. ⟨10.1016/j.neurol.2021.11.014⟩. |
| Publisher Information: |
HAL CCSD; Elsevier Masson |
| Publication Year: |
2022 |
| Collection: |
Université de Rennes 1: Publications scientifiques (HAL) |
| Subject Terms: |
Disease-modifying therapies; Mitoxantrone; Multiple sclerosis; [SDV.SPEE]Life Sciences [q-bio]/Santé publique et épidémiologie |
| Description: |
International audience ; Background: Six monthly courses of mitoxantrone were approved in France in 2003 for patients with highly active multiple sclerosis (MS).Objective: To report the 10-year clinical follow-up and safety of mitoxantrone as an induction drug followed by maintenance therapy in patients with early highly active relapsing-remitting MS (RRMS) and an Expanded Disability Status Scale (EDSS) score |
| Document Type: |
article in journal/newspaper |
| Language: |
English |
| Relation: |
info:eu-repo/semantics/altIdentifier/pmid/35181157; PUBMED: 35181157 |
| DOI: |
10.1016/j.neurol.2021.11.014 |
| Availability: |
https://ehesp.hal.science/hal-03588900; https://ehesp.hal.science/hal-03588900/document; https://ehesp.hal.science/hal-03588900/file/S0035378722000431.pdf; https://doi.org/10.1016/j.neurol.2021.11.014 |
| Rights: |
http://creativecommons.org/licenses/by-nc/ ; info:eu-repo/semantics/OpenAccess |
| Accession Number: |
edsbas.E4692BC9 |
| Database: |
BASE |