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Design, development, and local production of lipid-based nutritional supplements to enhance the complementary feeding diet:A model for collaboration for a feeding trial in Bangladesh

Title: Design, development, and local production of lipid-based nutritional supplements to enhance the complementary feeding diet:A model for collaboration for a feeding trial in Bangladesh
Authors: Merrill, Rebecca; de Pee, Saskia; Ahmed, Tahmeed; Kramer, Klaus; Hossain, Nahid; Choudhury, Nuzhat; Schumacher, Britta; Steiger, Georg; Minhas, Shahid; Shamim, Abu Ahmed; Shaikh, Saijuddin; Fuli, Rachel; Christian, Parul
Source: Merrill, R, de Pee, S, Ahmed, T, Kramer, K, Hossain, N, Choudhury, N, Schumacher, B, Steiger, G, Minhas, S, Shamim, A A, Shaikh, S, Fuli, R & Christian, P 2022, 'Design, development, and local production of lipid-based nutritional supplements to enhance the complementary feeding diet : A model for collaboration for a feeding trial in Bangladesh', Gates Open Research, vol. 6, 122. https://doi.org/10.12688/gatesopenres.13673.1
Publication Year: 2022
Collection: University of Bristol: Bristol Reserach
Subject Terms: /dk/atira/pure/core/keywords/exercise_nutrition_and_health_sciences; name=SPS Exercise; Nutrition and Health Sciences; /dk/atira/pure/core/keywords/faculty_of_social_sciences_and_law/sps_health_social_care_and_disability_research_centre; name=SPS Health Social Care and Disability Research Centre; Lipid-based nutrient supplements; Malnutrition; Maternal and child; Micronutrient; Multiagency collaboration
Description: Background: Lipid-based nutrient supplements (LNS) are effective for treating childhood wasting and for preventing stunting, wasting, and anemia, but large-scale production and programmatic use are a barrier. Locally-developed and produced LNS may be more affordable and reduce logistical procurement and importation hurdles, while promoting private sector engagement and partnership. Methods: In northwestern Bangladesh, we conducted a community-based trial of complementary food supplementation to test its efficacy to reduce childhood stunting. Two locally-developed, small-quantity LNS (20g/day, rice-lentil and chick-pea based) were designed, developed first at small scale in the 'kitchen' laboratory under controlled conditions, followed by taking them to a local food manufacturer for larger production for the study. We describe here the partnership, required expertise and capacity, experiences, and lessons learned that made this uniquely complex undertaking possible. Results: Key steps in the journey included addressing the dynamics of clear communication between partners, executing on carefully assigned tasks and roles, correcting course when needed, and maintaining timeliness and roadmaps. Knowledge of food science and technology was key in solving many food-production challenges that were encountered in taking the laboratory recipe to the factory. Factory production was established and had to meet quality and hygiene criteria set for young children. Conclusions: We provide documentation of this experience as a model to describe the various steps and considerations and what is entailed in local LNS production. We highlight the importance of a well-conceived collaboration with clear roles that created a 'win-win' situation for all partners for achieving common goals, establishing improved technology at the factory, and building new capacity to produce such products for children in a low resource setting.
Document Type: article in journal/newspaper
Language: English
Relation: info:eu-repo/semantics/altIdentifier/pmid/36381557; info:eu-repo/semantics/altIdentifier/hdl/https://hdl.handle.net/1983/797369d6-e1b5-467f-a1b7-eb949d053177
DOI: 10.12688/gatesopenres.13673.1
Availability: https://hdl.handle.net/1983/797369d6-e1b5-467f-a1b7-eb949d053177; https://research-information.bris.ac.uk/en/publications/797369d6-e1b5-467f-a1b7-eb949d053177; https://doi.org/10.12688/gatesopenres.13673.1; https://www.scopus.com/pages/publications/85141942453
Rights: info:eu-repo/semantics/openAccess ; http://creativecommons.org/licenses/by/4.0/
Accession Number: edsbas.E4DB6D6E
Database: BASE