Common genetic variation near the phospholamban gene is associated with cardiac repolarisation:meta-analysis of three genome-wide association studies
| Title: | Common genetic variation near the phospholamban gene is associated with cardiac repolarisation:meta-analysis of three genome-wide association studies |
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| Authors: | Nolte, IM; Wallace, C; Newhouse, Stephen; Waggott, D; Fu, J; Soranzo, N; Gwilliam, R; Deloukas, P; Savelieva, I; Zheng, D; Dalageorgou, C; Farrall, M; Samani, NJ; Connell, J; Dominiczak, A; Lathrop, M; Zeggini, E; Wain, LV; Newton-Cheh, C; Eijgelsheim, M; Rice, K; de Bakker, PI; Pfeufer, A; Sanna, S; Arking, DE; Asselbergs, FW; Spector, TD; Carter, ND; Jeffery, S; Tobin, M; Caulfield, M; Snieder, H; Paterson, AD; Munroe, PB; Jamshidi, YM |
| Source: | Nolte, IM, Wallace, C, Newhouse, S, Waggott, D, Fu, J, Soranzo, N, Gwilliam, R, Deloukas, P, Savelieva, I, Zheng, D, Dalageorgou, C, Farrall, M, Samani, NJ, Connell, J, Dominiczak, A, Lathrop, M, Zeggini, E, Wain, LV, Newton-Cheh, C, Eijgelsheim, M, Rice, K, de Bakker, PI, Pfeufer, A, Sanna, S, Arking, DE, Asselbergs, FW, Spector, TD, Carter, ND, Jeffery, S, Tobin, M & Caulfield, M & Snieder, H & Paterson, AD & Munroe, PB & Jamshidi, YM 2009, 'Common genetic variation near the phospholamban gene is associated with cardiac repolarisation : meta-analysis of three genome-wide association studies', PL o S .... |
| Publication Year: | 2009 |
| Collection: | King's College, London: Research Portal |
| Description: | To identify loci affecting the electrocardiographic QT interval, a measure of cardiac repolarisation associated with risk of ventricular arrhythmias and sudden cardiac death, we conducted a meta-analysis of three genome-wide association studies (GWAS) including 3,558 subjects from the TwinsUK and BRIGHT cohorts in the UK and the DCCT/EDIC cohort from North America. Five loci were significantly associated with QT interval at P |
| Document Type: | article in journal/newspaper |
| File Description: | application/pdf |
| Language: | English |
| ISSN: | 1932-6203 |
| Relation: | info:eu-repo/semantics/altIdentifier/eissn/1932-6203 |
| DOI: | 10.1371/journal.pone.0006138 |
| Availability: | https://kclpure.kcl.ac.uk/portal/en/publications/9158e0c8-a748-4433-a8e9-7f89b6edbb3d; https://doi.org/10.1371/journal.pone.0006138; https://kclpure.kcl.ac.uk/ws/files/56788381/Common_Genetic_Variation_Near_NEWHOUSE_Published_9Jul2009_GOLD_VoR.pdf |
| Rights: | info:eu-repo/semantics/openAccess ; http://creativecommons.org/licenses/by/4.0/ |
| Accession Number: | edsbas.E4F5F2EF |
| Database: | BASE |