| Title: |
Training in the fasted state improves glucose tolerance during fat-rich diet |
| Authors: |
Van Proeyen, K.; Szlufcik, K.; Nielens, H.; Pelgrim, K.; Deldicque, L.; Hesselink, M.K.C.; van Veldhoven, P P.; Hespel, P. |
| Source: |
Van Proeyen, K, Szlufcik, K, Nielens, H, Pelgrim, K, Deldicque, L, Hesselink, M K C, van Veldhoven, P P & Hespel, P 2010, 'Training in the fasted state improves glucose tolerance during fat-rich diet', Journal of Physiology, vol. 599, no. Pt21, pp. 4289-4302. https://doi.org/10.1113/jphysiol.2010.196493 |
| Publication Year: |
2010 |
| Collection: |
Maastricht University Research Publications |
| Description: |
Fat-rich energy-dense diet is an important cause of insulin resistance. Stimulation of fat turnover in muscle cells during dietary fat challenge may contribute to maintenance of insulin sensitivity. Exercise in the fasted state markedly stimulates energy provision via fat oxidation. Therefore, we investigated whether exercise training in the fasted state is more potent than exercise in the fed state to rescue whole-body glucose tolerance and insulin sensitivity during a period of hyper-caloric fat-rich diet. Healthy male volunteers (18-25y) received a hyper-caloric (~+30% kcal/day) fat-rich (50% of kcal) diet for 6 weeks. Part of the subjects performed endurance exercise training (4d/week) in the fasted state (F; n=10), whilst the others ingested carbohydrates before and during the training sessions (CHO; n=10). The control group did not train (CON; n=7). Body weight increased in CON (+3.0+/-0.8 kg) and CHO (+1.4+/-0.4 kg) (P |
| Document Type: |
article in journal/newspaper |
| File Description: |
application/pdf |
| Language: |
English |
| ISSN: |
0022-3751; 1469-7793 |
| Relation: |
info:eu-repo/semantics/altIdentifier/pmid/20837645; info:eu-repo/semantics/altIdentifier/wos/000283718800025; info:eu-repo/semantics/altIdentifier/pissn/0022-3751; info:eu-repo/semantics/altIdentifier/eissn/1469-7793 |
| DOI: |
10.1113/jphysiol.2010.196493 |
| Availability: |
https://cris.maastrichtuniversity.nl/en/publications/b209d7f9-2dad-4b7d-8023-6176eb8a4203; https://doi.org/10.1113/jphysiol.2010.196493; https://cris.maastrichtuniversity.nl/ws/files/75664844/Hesselink_2010_Training_in_the_fastest_state.pdf |
| Rights: |
info:eu-repo/semantics/openAccess ; https://umlib.nl/taverne-license |
| Accession Number: |
edsbas.E542FA94 |
| Database: |
BASE |