| Title: |
Odontoameloblastoma with extensive chondroid matrix deposition in a guinea pig |
| Authors: |
Wong, Hannah E; Hedley, Joanna; Stapleton, Nadene; Murphy, Brian; Priestnall, Simon L |
| Source: |
Journal of Veterinary Diagnostic Investigation, vol 30, iss 5 |
| Publisher Information: |
eScholarship, University of California |
| Publication Year: |
2018 |
| Collection: |
University of California: eScholarship |
| Subject Terms: |
3009 Veterinary Sciences (for-2020); 30 Agricultural; Veterinary and Food Sciences (for-2020); 3109 Zoology (for-2020); 31 Biological Sciences (for-2020); Dental/Oral and Craniofacial Disease (rcdc); 2.1 Biological and endogenous factors (hrcs-rac); Animals (mesh); Diagnosis; Differential (mesh); Fatal Outcome (mesh); Guinea Pigs (mesh); Male (mesh); Maxillary Neoplasms (mesh); Neoplasm Recurrence; Local (mesh); Odontogenic Tumors (mesh); Rodent Diseases (mesh); Species Specificity (mesh); Tomography; X-Ray Computed (mesh); Chondroid; guinea pigs; odontoameloblastoma; odontogenic mixed tumor |
| Subject Geographic: |
793 - 797 |
| Description: |
Odontoameloblastomas (previously incorporated within ameloblastic odontomas) are matrix-producing odontogenic mixed tumors and are closely related in histologic appearance to the 2 other types of matrix-producing odontogenic mixed tumors: odontomas and ameloblastic fibro-odontomas. The presence or absence of intralesional, induced non-neoplastic tissue must be accounted for in the diagnosis. Herein we describe a naturally occurring odontoameloblastoma with extensive chondroid cementum deposition in a guinea pig ( Cavia porcellus). Microscopically, the mass featured palisading neoplastic odontogenic epithelium closely apposed to ribbons and rings of a pink dental matrix (dentinoid), alongside extensive sheets and aggregates of chondroid cementum. The final diagnosis was an odontoameloblastoma given the abundance of odontogenic epithelium in association with dentinoid but a paucity of pulp ectomesenchyme. Chondroid cementum is an expected anatomical feature of cavies, and its presence within the odontoameloblastoma was interpreted as a response of the ectomesenchyme of the dental follicle to the described neoplasm. Our case illustrates the inductive capabilities of odontoameloblastomas while highlighting species-specific anatomy that has resulted in a histologic appearance unique to cavies and provides imaging and histologic data to aid diagnosis of these challenging lesions. |
| Document Type: |
article in journal/newspaper |
| File Description: |
application/pdf |
| Language: |
unknown |
| Relation: |
qt1hq6h65f; https://escholarship.org/uc/item/1hq6h65f; https://escholarship.org/content/qt1hq6h65f/qt1hq6h65f.pdf |
| DOI: |
10.1177/1040638718794784 |
| Availability: |
https://escholarship.org/uc/item/1hq6h65f; https://escholarship.org/content/qt1hq6h65f/qt1hq6h65f.pdf; https://doi.org/10.1177/1040638718794784 |
| Rights: |
public |
| Accession Number: |
edsbas.E543E4D5 |
| Database: |
BASE |