| Title: |
An unusual presentation in relapse case of histoid leprosy |
| Authors: |
Mathur, Mahesh; Paudel, Sumit; Bhattarai, Nabita; Regmi, Sandhya; Karki, Sambidha; Shrestha, Sharad |
| Source: |
Skin Health and Disease ; volume 5, issue 6, page 467-469 ; ISSN 2690-442X |
| Publisher Information: |
Oxford University Press (OUP) |
| Publication Year: |
2025 |
| Description: |
Histoid leprosy (HL) is a very rare and highly infectious variant of lepromatous leprosy, presenting as skin-coloured, succulent nodules and plaques on apparently healthy skin. It is histologically characterized by a dense bundle of histiocytes arranged in storiform manner. Usually, it occurs in patients with leprosy who relapse after dapsone monotherapy or inadequate antileprotic treatment; it can even arise de novo. We present a case of umbilicated presentation in a patient with a case of relapse HL, even after adequate treatment with multibacillary multidrug therapy for 12 months. Although rare, the higher load of lepra bacilli in these cases makes it a matter of concern, and challenging for leprologists to make early diagnosis and treatment. |
| Document Type: |
article in journal/newspaper |
| Language: |
English |
| DOI: |
10.1093/skinhd/vzaf067 |
| Availability: |
https://doi.org/10.1093/skinhd/vzaf067; https://academic.oup.com/skinhd/article-pdf/5/6/467/65006604/vzaf067.pdf |
| Rights: |
https://creativecommons.org/licenses/by/4.0/ |
| Accession Number: |
edsbas.E5516E5C |
| Database: |
BASE |