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Impact of 68Ga-DOTATOC PET/CT in comparison to 111In-Octreotide SPECT/CT in Management of Neuro-Endocrine Tumors: a case report

Title: Impact of 68Ga-DOTATOC PET/CT in comparison to 111In-Octreotide SPECT/CT in Management of Neuro-Endocrine Tumors: a case report
Authors: Anna Tolomeo; Gaetano Lopopolo; Dimiccoli Vincenzo; Luana Perioli; Antonio Scilimati; Sergio Modoni
Contributors: Tolomeo, Anna; Lopopolo, Gaetano; Vincenzo, Dimiccoli; Perioli, Luana; Scilimati, Antonio; Modoni, Sergio
Publication Year: 2020
Collection: IRIS Università degli Studi di Perugia
Subject Terms: Neuroendocrine tumour; PET/CT; 68Ga-DOTATOC; 18F-FDG; 111In-Octreotide; Ileo-cecal-NET
Description: Rationale:In the diagnostics of neuroendocrine tumors (NETs), scintigraphy and Single Photon Emission Computed Tomography/Computed Tomography (SPECT/CT) with 111Indium-Octreotide occupy a prominent place.The introduction in clinical practice of 68Gallium-labelled somatostatin analogues (DOTA-TOC, DOTA-TATE, DOTA-NOC) for Positron Emission Tomography/Computed Tomography (PET/CT), significantly improved NETs diagnostics due to greater sensitivity and improved lesion detection in addition to better patient convenience and decreased radiation dose.Patient concerns:We report a case of a patient who was diagnosed with a neuroendocrine tumor of the ileocecal valve.Diagnoses:Diagnosis was made by ultrasonography, CT, and colonoscopy. Hystology after surgery was G2 NET of ileo-cecal valve. Restaging was carried out by 111In-Octreotide SPECT/CT and, 1 month later, by 68Ga-DOTATOC PET/CT. 18F-FDG PET/C was also carried out.Interventions:68Ga-DOTATOC PET/CT showed larger disease that modified dise.
Document Type: article in journal/newspaper
File Description: STAMPA
Language: English
Relation: info:eu-repo/semantics/altIdentifier/pmid/32049844; volume:99; issue:7; firstpage:1; lastpage:5; numberofpages:5; journal:MEDICINE; https://hdl.handle.net/11391/1456721
DOI: 10.1097/MD.0000000000019162
Availability: https://hdl.handle.net/11391/1456721; https://doi.org/10.1097/MD.0000000000019162
Accession Number: edsbas.E5DE94BA
Database: BASE