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Evaluating the impact of financial navigation on financial catastrophe and distress for cancer care: a randomized control trial—COST-FIN

Title: Evaluating the impact of financial navigation on financial catastrophe and distress for cancer care: a randomized control trial—COST-FIN
Authors: Sohail, AH; Afolaranmi, O; Wuraola, FO; Caputo, M; Gutierrez, G; Oyewole, A; Ebekue, DO; Adegbite, ZO; Awe, C; Ogunniyi, T; Opeyemi, A; Nwankwo, C; Uwechue, F; Sherman, D; Lambert, CN; Adedayo, J; Diaz, K; Christian, EN; Abdulkareem, F; Akin-Adigun, O; Akingbola, A; Okeke, S; Knapp, G; Dare, A
Publisher Information: BioMed Central
Publication Year: 2026
Collection: Oxford University Research Archive (ORA)
Description: Background: As with most Sub-Saharan African countries, Nigeria has a rising incidence of cancer, with disproportionate mortality rates. The financial burden of cancer care often results in catastrophic healthcare spending, leading to treatment refusal, disruption, and discontinuation. This is particularly significant in Nigeria, where nearly all patients are uninsured, and out-of-pocket costs often exceed households’ ability to pay. Financial navigation programs (FNPs) have been shown to mitigate treatment-related financial toxicity in cancer care and reduce treatment abandonment, but there is a paucity of high-quality data on this intervention in resource-constrained settings. Here, we present a randomized controlled trial to evaluate the impact of a novel FNP in Nigeria. Methods: We designed the COST-FIN trial, a multi-site pragmatic single-blinded randomized controlled trial of newly diagnosed (
Document Type: article in journal/newspaper
Language: English
DOI: 10.1186/s13063-026-09480-2
Availability: https://doi.org/10.1186/s13063-026-09480-2; https://ora.ox.ac.uk/objects/uuid:574bf00c-5be3-4be4-bf89-ab4d38fb98d4
Rights: info:eu-repo/semantics/openAccess ; CC Attribution-NonCommercial-NoDerivatives (CC BY-NC-ND)
Accession Number: edsbas.E68BFA4D
Database: BASE