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Neoadjuvant Chemotherapy in Breast Cancer: Evaluation of the Impact on Surgical Outcomes and Prognosis

Title: Neoadjuvant Chemotherapy in Breast Cancer: Evaluation of the Impact on Surgical Outcomes and Prognosis
Authors: Corrado Chiappa; Maltecca Greta; Leoni Miriam; Giuseppe Ietto; Davide Inversini; Andrea Ballabio; Alice Bonetti; Alberto Mangano; Rossana Gueli; Giulio Carcano; Francesca Angela Rovera
Source: Cancers, Vol 16, Iss 13, p 2332 (2024)
Publisher Information: MDPI AG
Publication Year: 2024
Collection: Directory of Open Access Journals: DOAJ Articles
Subject Terms: breast cancer; neoadjuvant chemotherapy; conservative surgery; Neoplasms. Tumors. Oncology. Including cancer and carcinogens; RC254-282
Description: The correlation between TNM staging and histology variations in a sample of patients who underwent neoadjuvant chemotherapy demonstrates a positive impact on both increasing conservative surgery and achieving pCR, resulting in better outcomes in terms of disease-free survival (DFS) and the risk of relapse. Benefits have also been highlighted in terms of cosmetic outcomes, postoperative complications, and psychological benefits. However, the overall outcomes must be evaluated according to the subtype and individual characteristics of the patients.
Document Type: article in journal/newspaper
Language: English
Relation: https://www.mdpi.com/2072-6694/16/13/2332; https://doaj.org/toc/2072-6694; https://doaj.org/article/9eb1e635934744019ff811fd9eaff04b
DOI: 10.3390/cancers16132332
Availability: https://doi.org/10.3390/cancers16132332; https://doaj.org/article/9eb1e635934744019ff811fd9eaff04b
Accession Number: edsbas.E6D984AD
Database: BASE