| Title: |
In-Depth Characterization of Full-Length Archived Viral Genomes after Nine Years of Posttreatment HIV Control |
| Authors: |
Trémeaux, Pauline; Lemoine, Frédéric; Mélard, Adeline; Gousset, Marine; Boufassa, Faroudy; Orr, Sylvie; Monceaux, Valérie; Gascuel, Olivier; Lambotte, Olivier; Hocqueloux, Laurent; Saez-Cirion, Asier; Rouzioux, Christine; Avettand-Fenoel, Véronique; Bani-Sadr, Firouzé; Hentzien, Maxime; Berger, Jean-Luc; Kmiec, Isabelle; Pichancourt, Gilles; Nasri, Safa; Hittinger, Gilles; Lambry, Véronique; Beaudrey, Anne-Cécile; Pialoux, Gilles; Chas, Julie; Palacios, Christia; Adda, Anne; Viard, Jean Paul; Dulucq, Marie-Josée; Weiss, Laurence; Karmochkine, Marina; Meghadecha, Mohamed; Salmon-Ceron, Dominique; Piétri, Marie-Pierre; Blanche, Philippe; Molina, Jean-Michel; Taulera, Olivier; Ponscarme, Diane; Delgado Bertaut, Jeannine; Makhloufi, Djamila; Godinot, Matthieu; Artizzu, Valérie; Miailhes, Patrick; Cotte, Laurent; Pailhes, Sophie; Conrad, Anne; Karkowski, Ludovic; Ogoudjobi, Stanislas; Yazdanpanah, Yazdan |
| Contributors: |
Ueno, Takamasa; Agence Nationale de Recherches sur le Sida et les Hépatites Virales; HHS | National Institutes of Health |
| Source: |
Microbiology Spectrum ; volume 11, issue 1 ; ISSN 2165-0497 |
| Publisher Information: |
American Society for Microbiology |
| Publication Year: |
2023 |
| Description: |
Most people living with HIV need antiretroviral therapy to control their infection and experience viral relapse in case of treatment interruption, because of viral reservoir (proviruses) persistence. Knowing that proviruses are very diverse and most of them are defective in treated individuals, we aimed to characterize the HIV blood reservoirs of posttreatment controllers (PTCs), rare models of drug-free remission, in comparison with spontaneous controllers and treated individuals. |
| Document Type: |
article in journal/newspaper |
| Language: |
English |
| DOI: |
10.1128/spectrum.03267-22 |
| Availability: |
https://doi.org/10.1128/spectrum.03267-22; https://journals.asm.org/doi/pdf/10.1128/spectrum.03267-22 |
| Rights: |
https://creativecommons.org/licenses/by/4.0/ ; https://journals.asm.org/non-commercial-tdm-license |
| Accession Number: |
edsbas.E737A56 |
| Database: |
BASE |