| Title: |
Discovery of AG-120 (Ivosidenib): A First-in-Class Mutant IDH1 Inhibitor for the Treatment of IDH1 Mutant Cancers |
| Authors: |
Popovici-Muller, Janeta; Lemieux, René M.; Artin, Erin; Saunders, Jeffrey O.; Salituro, Francesco G.; Travins, Jeremy; Cianchetta, Giovanni; Cai, Zhenwei; Zhou, Ding; Cui, Dawei; Chen, Ping; Straley, Kimberly; Tobin, Erica; Wang, Fang; David, Muriel D.; Penard-Lacronique, Virginie; Quivoron, Cyril; Saada, Véronique; de Botton, Stéphane; Gross, Stefan; Dang, Lenny; Yang, Hua; Utley, Luke; Chen, Yue; Kim, Hyeryun; Jin, Shengfang; Gu, Zhiwei; Yao, Gui; Luo, Zhiyong; Lv, Xiaobing; Fang, Cheng; Yan, Liping; Olaharski, Andrew; Silverman, Lee; Biller, Scott; Su, Shin-San M.; Yen, Katharine |
| Contributors: |
Association pour la Recherche sur le Cancer; Ligue Contre le Cancer; Minist?re des Affaires Sociales et de la Sant; Institut National Du Cancer; Minist?re de l'Education Nationale, de l'Enseignement Superieur et de la Recherche; Agios Pharmaceuticals Inc. |
| Source: |
ACS Medicinal Chemistry Letters ; volume 9, issue 4, page 300-305 ; ISSN 1948-5875 1948-5875 |
| Publisher Information: |
American Chemical Society (ACS) |
| Publication Year: |
2018 |
| Document Type: |
article in journal/newspaper |
| Language: |
English |
| DOI: |
10.1021/acsmedchemlett.7b00421 |
| Availability: |
https://doi.org/10.1021/acsmedchemlett.7b00421; http://pubs.acs.org/doi/pdf/10.1021/acsmedchemlett.7b00421; https://pubs.acs.org/doi/pdf/10.1021/acsmedchemlett.7b00421 |
| Rights: |
http://pubs.acs.org/page/policy/authorchoice_termsofuse.html |
| Accession Number: |
edsbas.E75D33D4 |
| Database: |
BASE |