| Title: |
Management of Patients with Diabetic Macular Edema Switched from Dexamethasone Intravitreal Implant to Fluocinolone Acetonide Intravitreal Implant |
| Authors: |
Baillif, Stéphanie; Staccini, Pascal; Weber, Michel; Delyfer, Marie-Noëlle; Le Mer, Yannick; Gualino, Vincent; Collot, Laurence; Merite, Pierre-Yves; Creuzot-Garcher, Catherine; Kodjikian, Laurent; Massin, Pascale |
| Contributors: |
Hôpital Pasteur Nice (CHU); Université Côte d'Azur (UniCA); Centre Hospitalier Universitaire de Nantes = Nantes University Hospital (CHU Nantes); Centre Hospitalier Universitaire de Bordeaux (CHU Bordeaux); Bordeaux population health (BPH); Université de Bordeaux (UB)-Institut de Santé Publique, d'Épidémiologie et de Développement (ISPED)-Institut National de la Santé et de la Recherche Médicale (INSERM); Fondation Ophtalmologique Adolphe de Rothschild Paris; Clinique Honoré-Cave, Montauban; Centre Hospitalier de Chaumont; Centre d'Ophtalmologie AIX VISION; Service d'Ophtalmologie (CHU de Dijon); Centre Hospitalier Universitaire de Dijon - Hôpital François Mitterrand (CHU Dijon); Centre des Sciences du Goût et de l'Alimentation Dijon (CSGA); Université de Bourgogne (UB)-Centre National de la Recherche Scientifique (CNRS)-Institut National de Recherche pour l’Agriculture, l’Alimentation et l’Environnement (INRAE)-Institut Agro Dijon; Institut national d'enseignement supérieur pour l'agriculture, l'alimentation et l'environnement (Institut Agro)-Institut national d'enseignement supérieur pour l'agriculture, l'alimentation et l'environnement (Institut Agro); Hospices Civils de Lyon (HCL); Centre d'Ophtalmologie Breteuil |
| Source: |
ISSN: 1999-4923 ; Pharmaceutics ; https://hal.inrae.fr/hal-03854968 ; Pharmaceutics, 2022, 14 (11), pp.2391. ⟨10.3390/pharmaceutics14112391⟩ ; https://www.mdpi.com/1999-4923/14/11/2391. |
| Publisher Information: |
CCSD; MDPI |
| Publication Year: |
2022 |
| Collection: |
HAL Université Côte d'Azur |
| Subject Terms: |
dexamethasone implant; diabetic macular edema; fluocinolone acetonide implant; intravitreal therapy; [SDV.MHEP]Life Sciences [q-bio]/Human health and pathology; [SDV.MHEP.OS]Life Sciences [q-bio]/Human health and pathology/Sensory Organs |
| Description: |
International audience ; To assess anatomical and functional outcomes after switching from dexamethasone implant (DEXi) to fluocinolone acetonide implant (FAci) in 113 diabetic macular edema eyes, a multicentric retrospective observational study was conducted. Seventy-five eyes (73.5%) were switched 1–8 weeks after their last DEXi. The mean best-corrected visual acuity improved to 59.8 letters at month 4 and remained stable during the follow-up. The mean central macular thickness (CMT) significantly decreased during the follow-up, with a minimum of 320.9 μm at month 3. The baseline CMT was higher in eyes that received the last DEXi >8 weeks versus |
| Document Type: |
article in journal/newspaper |
| Language: |
English |
| Relation: |
info:eu-repo/semantics/altIdentifier/pmid/36365209; PUBMED: 36365209; WOS: 000883992000001 |
| DOI: |
10.3390/pharmaceutics14112391 |
| Availability: |
https://hal.inrae.fr/hal-03854968; https://hal.inrae.fr/hal-03854968v1/document; https://hal.inrae.fr/hal-03854968v1/file/baillif_2022_vol14_2391_pharmaceutics.pdf; https://doi.org/10.3390/pharmaceutics14112391 |
| Rights: |
https://creativecommons.org/licenses/by/4.0/ ; info:eu-repo/semantics/OpenAccess |
| Accession Number: |
edsbas.E79BC824 |
| Database: |
BASE |